Recombinant vaccine for diseases caused by encapsulated organisms

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dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.en
dc.contributor.inventorInzana, Thomas J.en
dc.contributor.inventorWard, Christineen
dc.date.accessed2016-08-19en
dc.date.accessioned2016-08-24T17:54:11Zen
dc.date.available2016-08-24T17:54:11Zen
dc.date.filed1996-06-27en
dc.date.issued2000-07-11en
dc.description.abstractVaccines for diseases caused by normally encapsulated organisms are produced by genetically modifying those organisms by deleting the genes encoding for capsule synthesis or a portion thereof sufficient to produce non-capsulated mutants of the organisms. As an example, a live, attenuated strain of Actinobacillus pleuropneumoniae genetically modified with a large deletion in a chromosomal regions of the DNA which encodes for capsule synthesis is a safe and effective vaccine against swine pleuropneumonia.en
dc.format.mimetypeapplication/pdfen
dc.identifier.applicationnumber8673814en
dc.identifier.patentnumber6086894en
dc.identifier.urihttp://hdl.handle.net/10919/72420en
dc.identifier.urlhttp://pimg-fpiw.uspto.gov/fdd/94/868/060/0.pdfen
dc.language.isoen_USen
dc.publisherUnited States Patent and Trademark Officeen
dc.subject.cpcA61K39/0002en
dc.subject.cpcA61K39/102en
dc.subject.cpcA61K2039/522en
dc.subject.cpcA61K2039/552en
dc.subject.cpcC07K14/285en
dc.subject.cpcY10S424/825en
dc.subject.uspc424/235.1en
dc.subject.uspcother424/93.2en
dc.subject.uspcother424/256.1en
dc.subject.uspcother424/825en
dc.subject.uspcother435/243en
dc.subject.uspcother435/245en
dc.subject.uspcother435/252.3en
dc.subject.uspcother435/440en
dc.subject.uspcother435/471en
dc.titleRecombinant vaccine for diseases caused by encapsulated organismsen
dc.typePatenten
dc.type.dcmitypeTexten
dc.type.patenttypeutilityen

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