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2-aroyl-4-acyl paclitaxel (Taxol) analogs

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6476242.pdf (1.42 MB)
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Date

2002-11-05

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United States Patent and Trademark Office

Abstract

2-debenzoyl-4-deacetyl paclitaxel, antineoplastic analogs thereof and intermediates are taught, as well as the formation of the compound, analogs and intermediates. The compound, analogs and intermediates may be used to form pharmaceutical compositions having anti-neoplastic activity. Further, the compound, analogs and intermediates may be used to treat cancer when applied in an effective amount by means such as a pharmaceutical composition.

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