Browsing by Author "Carreon, Analyn C."
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- Cationic Polythiophenes as Responsive DNA-Binding PolymersCarreon, Analyn C.; Santos, Webster L.; Matson, John B.; So, Regina C. (The Royal Society of Chemistry, 2013-09-23)A new water soluble cationic polythiophene derivative, poly(N,N,N-trimethyl-3-(2-(thiophen-3-yl)acetamido)propan-1-aminium iodide), was synthesized via two consecutive post-polymerization functionalizations of poly(methyl 2-(thiophen-3-yl)acetate). This conjugated polymer binds DNA at N/P = 5 and forms polyplexes at N/P = 10. Its potential use as a theranostic gene delivery vehicle is investigated here.