Bradley Department of Electrical and Computer Engineering

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https://hdl.handle.net/10919/18738
From pervasive computing, to smart power systems, Virginia Tech ECE faculty and students delve into all major areas of electrical and computer engineering. The main campus is in Blacksburg, and the department has additional research and teaching facilities in Arlington, Falls Church, and Hampton, Virginia.

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Browsing Bradley Department of Electrical and Computer Engineering by Department "Aerospace and Ocean Engineering"

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    Increase in Stability of an X-Configured AUV through Hydrodynamic Design Iterations with the Definition of a New Stability Index to Include Effect of Gravity
    Miller, Lakshmi; Brizzolara, Stefano; Stilwell, Daniel J. (MDPI, 2021-08-30)
    A study about the effect of different configurations of stationary and movable appendages on the dynamic stability of an autonomous underwater vehicle (AUV) is presented. A new stability index that can be used to assess dynamic stability in the vertical plane is derived. It improves upon the vertical plane stability index by accurately accounting for the contribution of hydrostatic forces to dynamic stability, even at low speeds. The use of the new stability index is illustrated by applying it to a set of AUV configurations based on an AUV initially designed at Virginia Tech and built by Dive Technologies. The applicability of this index depends on the speed of the craft. The range of applicability in terms of speed is presented for the DIVE craft as an example. The baseline design of the DIVE craft has asymmetry in the vertical plane and symmetry in the horizontal plane. A virtual planar motion mechanism (VPMM) is used to obtain the hydrodynamic coefficients of the hull. Design iterations are performed on the baseline design by varying the appendages in shape and size, adding appendages and adding features on appendages. The best and the baseline design from this effort are incorporated in a 6 DOF lumped-parameter model (LPM) to compare results of a straight line maneuver. A computational fluid dynamic (CFD) tool is used to obtain the trajectory comparison of turn-circle maneuver for these two designs. A principal conclusion is the important contribution of a hydrostatic restoring force at low-moderate speeds by using GVgrav and the influence of design of control surfaces, both stationary and non-stationary, in the achievement of control-fixed course stability.
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    A Stochastic Model Correctly Predicts Changes in Budding Yeast Cell Cycle Dynamics upon Periodic Expression of CLN2
    Oguz, Cihan; Palmisano, Alida; Laomettachit, Teeraphan; Watson, Layne T.; Baumann, William T.; Tyson, John J. (PLOS, 2014-05-09)
    In this study, we focus on a recent stochastic budding yeast cell cycle model. First, we estimate the model parameters using extensive data sets: phenotypes of 110 genetic strains, single cell statistics of wild type and cln3 strains. Optimization of stochastic model parameters is achieved by an automated algorithm we recently used for a deterministic cell cycle model. Next, in order to test the predictive ability of the stochastic model, we focus on a recent experimental study in which forced periodic expression of CLN2 cyclin (driven by MET3 promoter in cln3 background) has been used to synchronize budding yeast cell colonies. We demonstrate that the model correctly predicts the experimentally observed synchronization levels and cell cycle statistics of mother and daughter cells under various experimental conditions (numerical data that is not enforced in parameter optimization), in addition to correctly predicting the qualitative changes in size control due to forced CLN2 expression. Our model also generates a novel prediction: under frequent CLN2 expression pulses, G1 phase duration is bimodal among small-born cells. These cells originate from daughters with extended budded periods due to size control during the budded period. This novel prediction and the experimental trends captured by the model illustrate the interplay between cell cycle dynamics, synchronization of cell colonies, and size control in budding yeast.