Posters, Symposia, etc., School of Biomedical Engineering and Sciences

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https://hdl.handle.net/10919/56516

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Browsing Posters, Symposia, etc., School of Biomedical Engineering and Sciences by Subject "3D analysis"

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    Bioluminescence Tomography - Inner-light, Insight from Infrared
    Wang, Ge (2008-06-12)
    Bioluminescence tomography (BLT) is a molecular imaging modality, which derives a bioluminescent source distribution inside a small animal from external bioluminescent signals. We published the first paper on BLT in 2004 using the modality fusion approach. The introduction of BLT can be compared to the development of x-ray CT based on radiography. Without BLT, bioluminescent imaging is basically qualitative. With BLT, quantitative and 3D analyses become feasible inside a living mouse, which reveal important molecular and cellular information for numerous preclinical applications. *Complimentary film demonstrates 3D analysis of a living mouse with bioluminescent source
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    Results in the Past
    Wang, Ge (2010-02-04)
    Past research results include the following: • Modern CT scanners that use spiral-beam scanning and perform >100-million scans annually in the USA • Construction of the only 500nm resolution micro-CT system on the East Coast and the only 50nm nano-CT system with the interior tomography capability in the world from inside the walls of SAM-CT x-ray imaging facility • With further promise to handle large objects, reduce radiation dose, and improve temporal resolution, Interior tomography has already been extended to SPECT, MRI and other imaging modalities • A 3D analysis of the underlying molecular/cellular activities is taken from a mouse subject with an embedded bioluminescent source after an imaging model is built, linking the bioluminescent measurement and the source distribution.