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  • Impact of maternal obesity and mode of delivery on the newborn skin and oral microbiomes
    Seifert, Allison; Ingram, Kelly; Eko, Embelle Ngalame; Nunziato, Jaclyn; Ahrens, Monica; Howell, Brittany R. (Microbiology Society, 2025-04-10)
    Introduction. Previous studies have shown vast differences in the skin and oral microbiomes of newborns based on delivery method [Caesarean section (C-section) vs vaginal]. Exposure to or absence of certain bacteria during delivery can impact the neonate’s future susceptibility to infections, allergies or autoimmunity by altering immune functions. Few studies have focused on the impact of maternal obesity on the variations of newborn skin and oral microbiomes. Obese pregnant women typically have a higher vaginal microbiome diversity, and their pregnancies are at higher risk for adverse outcomes and complications. Hypothesis. We hypothesized that the skin and oral microbiomes of newborns born to obese mothers would include more diverse, potentially pathogenic bacteria and that the skin and oral microbiome in C-section delivered newborns would be less diverse than vaginally delivered newborns. Aim. We aim to begin to establish maternal obesity and mode of delivery as factors contributing to increased risk for negative newborn outcomes through impacts on newborn bacterial dysbiosis. Methodology. A skin swab was collected immediately following delivery of 39 newborns from 13 healthy weight body mass index (BMI 18.50–24.99), 11 overweight (BMI 25.0–29.99) and 15 obese (BMI ≥30.00) pregnant participants. An oral swab was collected immediately following delivery for 38 of these newborns from 13 healthy weight, 10 overweight and 15 obese pregnant participants. Bacterial genera were identified via 16S rRNA amplicon sequencing. Results. The newborn skin microbiome was comprised of typical skin bacteria (i.e. Corynebacterium). Newborns of obese participants had a higher relative abundance of Peptoniphilus in their skin microbiome compared to newborns of healthy weight participants (P=0.007). Neonates born via C-section had a higher relative abundance of Ureaplasma in their oral microbiome compared to neonates delivered vaginally (P=0.046). Conclusion. We identified differences in the newborn skin and oral microbiomes based on pre-pregnancy BMI and method of delivery. These differences could be linked to an increased risk of allergies, autoimmune disease and infections. Future longitudinal studies will be crucial in determining the long-term impact of these specific genera on newborn outcomes. Understanding these connections could lead to targeted interventions that reduce the risk of adverse outcomes and improve overall health trajectory.
  • A mindfulness-based multicomponent caregiver intervention (PAACC): Objectives, study design and cohort description
    Sapra, Mamta; Hagemann, Lauren; Luci, Katherine; Savla, Jyoti (Wiley, 2025-03)
    INTRODUCTION: Effective interventions are needed to reduce caregiver burden and stress, particularly among family caregivers of veterans with dementia. Unique risk factors such as traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) further complicate caregiving. This study compares a four-session mindfulness-based multicomponent intervention (PAACC) with a cognitive behavioral intervention (REACH), both designed to alleviate caregiver burden, and provides a baseline evaluation of caregivers in the intervention. A two-arm, blinded, randomized controlled trial assigned 133 dementia caregivers to PAACC (n = 67) or REACH (n = 66). Baseline assessments included caregiver stress, burden, mindfulness receptivity, rumination, compassion, depressive symptoms, anxiety, and care recipient behavior. Participants averaged 67.17 years, 85% were women, and 70% were spousal caregivers. Caregivers in PAACC reported higher depressive symptoms and anxiety and lower mindfulness receptivity. This study introduces the first mindfulness-based intervention for veteran caregivers, designed to enhance cognitive flexibility, cultivate compassion, and provide practical skills to improve quality of life. METHODS: The study utilized a two-arm, blinded, prospective randomized controlled trial to compare the PAACC and REACH interventions. A total of 133 dementia caregivers experiencing moderate to severe caregiver burden were assigned to receive either the PAACC intervention (n = 67) or the REACH intervention (n = 66). Baseline evaluations included caregiver stress, burden, mindfulness receptivity, rumination, compassion, depressive symptoms, anxiety, and the memory and behavior problems of the veteran living with dementia, using widely accepted measures from caregiving literature. RESULTS: Baseline assessments were conducted on 133 family caregivers of veterans living with dementia. The average caregiver age was 67.17 years (SD = 9.8), 85% were women, and 70% were spousal caregivers. No significant demographic differences were found between the two intervention groups. However, baseline comparisons showed that caregivers in the PAACC intervention reported higher depressive symptoms and anxiety, and lower mindfulness receptivity. A detailed protocol for the mindfulness-based multicomponent caregiver intervention PAACC is described. DISCUSSION: There is a growing need for multicomponent, skill-building interventions tailored for dementia caregivers who are at high risk of stress. This study introduces the first mindfulness-based intervention specifically for caregivers of veterans, designed to enhance cognitive flexibility, cultivate compassion, and equip caregivers with practical skills to improve their quality of life. Highlights: PAACC is a mindfulness-based multicomponent intervention for dementia caregivers of veterans. No demographic differences suggest psychological differences are not due to demographics. Baseline mental health and mindfulness readiness may impact intervention effectiveness.
  • 3D-Printed Wearable Biosensors for Livestock Health Monitoring
    Ali, Md Azahar; Howell, Brittany R.; Zhang, Liqing (IEEE, 2025-07)
    Livestock health monitoring stands as a linchpin in ensuring both the welfare of animals and the optimization of productivity. As we navigate toward meeting current and future food crises, the role of biosensors in this context cannot be overstated. Such biosensors serve as indispensable tools, offering real-time insights into the health status of livestock, thereby enabling early detection of diseases and prompt intervention. In addressing the challenges and potential of biosensors for livestock sensing, it is clear that while biosensors have seen extensive use in human health monitoring, their application in livestock is crucial for ensuring animal well-being and productivity, vital in meeting global food demands. To maximize effectiveness, there is a need for advanced manufacturing to develop customized, user-friendly, and cost-effective sensors. By harnessing the synergistic potential of electrochemical biosensors and advanced manufacturing, this review discusses the challenges that currently impede the widespread adoption of wearable electrochemical biosensors, advanced manufacturing techniques, and artificial intelligence in livestock sensing. This strategic approach not only bolsters animal welfare and productivity but also fortifies agricultural resilience in the face of evolving global food demands. This review highlights recent advancements in biosensors for livestock monitoring.
  • Maternal Essentialism and Preschoolers’ Executive Functioning: Indirect Effects Through Parenting Stress and Behavior
    McGregor, Casey M.; Arditti, Joyce A.; Shannon, Rachel B.; Blalock, Jamie (MDPI, 2025-10-25)
    Intensive mothering is a widespread cultural ideology positioning mothers as uniquely responsible for their children’s optimal development through emotionally and cognitively intensive caregiving. A key belief within this framework is maternal essentialism, which asserts that mothers are biologically and morally best suited for parenting young children. Guided by the Family Stress–Proximal Process (FSPP) model, this study examined whether maternal essentialist beliefs act as distal sociocultural stressors influencing children’s executive functioning indirectly through parenting stress and positive parenting behaviors. Data were collected via self-report from 255 U.S. mothers of 3- to 5-year-old children. Path analyses showed that stronger maternal essentialism was associated with increased parenting stress, which predicted lower engagement in positive parenting and greater reported difficulties in children’s executive functioning. The indirect effect of maternal essentialism on children’s executive functioning was statistically significant. These findings suggest that internalized cultural ideologies, often viewed as aspirational, may inadvertently increase parenting stress and reduce caregiving quality, which is associated with diminished child cognitive outcomes. This study extends prior research by linking maternal essentialist beliefs to child developmental outcomes through specified psychological and relational processes, supporting the usefulness of the FSPP framework in understanding how sociocultural pressures influence family dynamics and child development.
  • Long-Term Alterations of Glucocorticoid Receptor Expression and CD4+ T Cells in Adolescent Rhesus Macaques Following Early-Life Adversity
    Sanchez, Mar M.; Panagiotakopoulos, Leonidas; Hayes, Timothy; Howell, Brittany R.; Ethun, Kelly; Easley, Kirk A.; Silvestri, Guido; Carnathan, Diane G.; McCandless, Jackson; Meyer, Jerrold; Neigh, Gretchen N. (MDPI, 2025-12-05)
    Child maltreatment (MALT) is a devastating form of early-life adversity (ELA) and a primary risk for mental and physical illness. It is difficult to disentangle postnatal caregiving effects from heritable factors. Here we investigated the long-term effects of maternal care using a cross-fostering design to control for biological/heritable factors on immune function and inflammation during adolescence in a translational and naturalistic macaque model of MALT. We studied the impact of MALT on the immunophenotype of peripheral blood mononuclear cells (PBMCs) and assessed glucocorticoid receptor expression and function during adolescence. MALT was associated with elevated expression of NR3C1, the gene that encodes for the glucocorticoid receptor, in PBMCs. Glucocorticoid receptor function was not altered by MALT when examined for response to dexamethasone (DEX). In addition, MALT led to a reduction in the percentage of naïve CD4+ T cells and an increase in the percentage of central memory (Tcm) CD4+ T cells. These results suggest that MALT-exposed adolescents show residual effects of MALT on CD4+ T cells and increased expression of NR3C1 without demonstration of increased function of the glucocorticoid receptor. Taken together, these results suggest that ELA has enduring implications for cellular glucocorticoid receptor biology and CD4+ T cells.
  • Self-Reported ADHD Symptoms and Cognitive Performance in a National Sample of US Older Adults
    Mansoor, Marrium; Breaux, Rosanna; Lee, Tae-Ho; Katz, Benjamin (SAGE Publications, 2025-12)
    Objective: Although inattention symptoms have been previously linked to cognitive performance in younger samples, few studies have examined links between ADHD symptoms and cognitive performance for middle aged and older adults. Methods: In this study, we drew from a nationally representative sample from the Health and Retirement Study (HRS) of ~1,400 middle to older adults (Mage = 66.9, SD = 8.4; 41.4% male; 60.7% White) who completed a set of cognitive measures and an ADHD symptomatology questionnaire in the 2016 Wave of the HRS. A multigroup path model was run by examining the association between self-reported ADHD symptom subscale scores for inattention and hyperactivity/impulsivity as well as self-reported depressive symptoms and cognitive outcomes across three groups: middle age, young-old, and middle-old. Results: Inattention symptoms were significantly associated with Serial 7s and Immediate Recall, however the constrained model was the best fitting model, suggesting no differences in the associations between self-reported inattention symptoms and cognitive outcomes by age. Conclusion: These results are consistent with previous work on the links between ADHD symptoms and cognitive performance in younger populations and add to the literature on ADHD in later life. This may have implications for clinicians and practitioners as well as future research on older adults with ADHD.
  • The Questions, Challenges, and Possibilities When Joining Critical Disabilities Studies and Healthcare Research
    Toman, Madelyn; Atanasio, Meredith; Teaster, Pamela B. (MDPI, 2025-11-15)
    Background/Objectives: Interdisciplinary research teams that include critical disability studies (CDS) scholars and Healthcare and Medical Researchers have the potential to investigate complex lived experiences and explore new opportunities to best serve disabled communities. However, individuals in these fields typically approach disability research in different ways. Throughout this manuscript, we refer to a hypothetical interdisciplinary research team as an example of how to integrate the questions, challenges, and possibilities into practice when joining CDS and Healthcare and Medical Research. Discussion: First, we raise three large and complex questions that researchers must address (and discuss) when conducting disability research: (a) what is (a) disability, (b) what does it mean to live with a disability, and (c) who is included in research samples/as research participants for disability research? Then, we discuss the colliding and harmful relationship history between CDS and Healthcare and Medical Research fields, and the continued oppositional training of professionals in both fields. Finally, we offer insights into how collaborative efforts and methods of interdisciplinary research teams can optimize success when tackling complex research questions to serve disabled communities. Conclusions: We suggest approaches for projects at the intersection of CDS and Healthcare and Medical Research: holistic, person-centered research, treating individuals in the disability community as experts, and collaborating with the community while conducting research. This manuscript serves as a starting point for researcher teams looking to conduct ethical, rigorous, and trustworthy research at the intersection of health, medicine, and disability.
  • The Influence of Ultraprocessed Food Consumption on Energy Intake in Emerging Adulthood: A Controlled Feeding Trial
    Rego, Maria L. M.; Leslie, Emma; Schmall, Emily; Capra, Bailey; Hudson, Summer; Ahrens, Monica L.; Katz, Benjamin; Davy, Kevin P.; Hedrick, Valisa E.; DiFeliceantonio, Alexandra G.; Davy, Brenda M. (Wiley, 2025-11-19)
    OBJECTIVE: This study examined the impact of a 2-week eucaloric diet high in ultraprocessed foods (UPF) compared to a diet without UPF (non-UPF) on ad libitum energy intake (EI) and food selection in individuals aged 18-25. METHODS: In a randomized, crossover, proof-of-concept trial, participants completed two 14-day controlled feeding periods (81% UPF vs. 0% UPF), with a 4-week washout. Diets were matched for macronutrients, fiber, added sugar, diet quality, and energy density. Following each condition, participants consumed an ad libitum buffet meal including UPF and non-UPF. Energy and food grams consumed were quantified. Statistical analyses were conducted for the full sample, late adolescents (aged 18-21), and young adults (aged 22-25). RESULTS: Twenty-seven individuals aged 22 ± 2 years (mean BMI = 24 ± 3 kg/m2) were included. Diet compliance was ~99% overall. There was no effect of diet condition on meal total kcal or grams consumed or UPF or non-UPF consumption in the full sample (all p > 0.05). In the exploratory age subgroup analysis, an interaction between diet and age was observed for total EI (p < 0.001), where total EI increased among adolescents following the UPF diet (p = 0.03, d = 0.79), but not in young adults. CONCLUSIONS: Late adolescents may be susceptible to increased EI following a UPF diet. Future trials are warranted to evaluate this possibility. TRIAL REGISTRATION: ClinicalTrials.gov: NCT05550818.
  • Narratives of Personal Health and Sexual Education Experiences of Emerging Adults with Disabilities
    Toman, Madelyn; Wesche, Rose; Shivers, Carolyn (Springer, 2024-12-01)
    Disabled communities' sexualities have been historically oppressed. Currently in the U.S., public school curricula do not include inclusive sexual education and students with disabilities are often left out of classrooms that discuss any amount of personal health and sexual education (PHSE). Research on the disabled population is filled with samples of non-disabled individuals imposing their opinions on a population that they do not belong to. The purpose of this study was to capture lived experiences of ways emerging adults with disabilities learned about PHSE. Individuals with varied disabilities were intentionally included to add breadth to the research field. The final sample consisted of eight individuals (75% female, 87% White, mean age of 21.5). After conducting narrative interviews and analyses, four story types were generated: (1) "The Self-Guided Journey", (2) "Experience is the Best Teacher", (3) "Personal Health Matters More", and (4) "Two Ears, One Mouth". Our findings highlighted the lack of formal support and access to adequate, relevant information about sexuality for disabled communities. Informal sources, like families and media, sometimes served as helpful resources for PHSE and disabilities. Individuals' disability symptoms and personal characteristics need to be considered when crafting universally applicable personal health and sexuality education.
  • Reimagining stagnant perspectives of family structure: Advancing a critical theoretical research agenda
    Sanner, Caroline; Williams, Deadric T.; Mitchell, Sarah; Jensen, Todd M.; Russell, Luke T.; Garnett-Deakin, Aran (Wiley, 2024-12-01)
    Many Americans believe that a breakdown in the "traditional" two-married-parent family and the rise in single-parent families are responsible for persistent family inequality. The general argument is that children do best when they are raised by both biological parents. Evidence increasingly calls into question conventional wisdom about the universal benefits of the two-parent family, yet mainstream approaches to studying family structure continue to reinforce oversimplistic interpretations of the impact of family structure on well-being. In this article, we reconsider long-standing assumptions about the superiority of the heteropatriarchal two-married-parent family using historical and contemporary evidence to offset the stagnant theorizing in the study of family structure. We argue that, in pursuit of better science, family researchers must commit to theoretical approaches that move us beyond conventional perspectives of families toward critical perspectives that guide more nuanced, holistic, and contextualized analyses of how family structure actually operates in people's lives.
  • Parent and adolescent perspectives on family problems during the COVID-19 pandemic: Implications for family resilience
    Allen, Katherine R.; Crossler, Robert E.; Belanger, France; Resor, Jessica; Kissel, Heather A. (Wiley, 2025-02-01)
    Objective: To understand how parents and adolescents perceive the major family problems they faced during a global pandemic, focusing on implications for family resilience. Background: Families are challenged by the upheaval in contemporary life due to a global health pandemic and unrelenting changes to work, school, civic, and home routines. Family resilience theory guided our understanding of how families perceive and understand the problems they faced during a major disruption in their lives. Method: A diverse sample of parent-adolescent pairs was surveyed at two points in time. Qualitative content analysis was used to analyze open-ended questions asking about family members' perceptions of the major problems they faced as a family during the pandemic. Results: Most participants reported a major family problem during the pandemic (e.g., unemployment, online learning, isolation, fear of COVID-19), with financial issues being the most prevalent problem. Parents were more likely to identify a major family tension, compared with adolescents, who were more likely to say they were unaware of any major family problems. Conclusion: Parents and adolescents reported substantial family stress and tension, especially around financial strain and social isolation, indicating their heightened awareness of the new risks they were facing. Both parents and adolescents also described a willingness to pull together on behalf of family well-being and adaptation. Implications: Support mechanisms through public policy and from family life practitioners can help families navigate pandemic-related stressors, assess adverse events in adolescence, promote new pathways in navigating disrupted routines, and enhance family resilience.
  • An ode to fetal, infant, and toddler neuroimaging: Chronicling early clinical to research applications with MRI, and an introduction to an academic society connecting the field
    Pollatou, Angeliki; Filippi, Courtney A.; Aydin, Ezra; Vaughn, Kelly; Thompson, Deanne; Korom, Marta; Dufford, Alexander J.; Howell, Brittany; Zöllei, Lilla; Di Martino, Adriana; Graham, Alice; FIT’NG Group; Scheinos, Dustin; Spann, Marisa N. (Elsevier, 2022-02-07)
    Fetal, infant, and toddler neuroimaging is commonly thought of as a development of modern times (last two decades). Yet, this field mobilized shortly after the discovery and implementation of MRI technology. Here, we provide a review of the parallel advancements in the fields of fetal, infant, and toddler neuroimaging, noting the shifts from clinical to research use, and the ongoing challenges in this fast-growing field. We chronicle the pioneering science of fetal, infant, and toddler neuroimaging, highlighting the early studies that set the stage for modern advances in imaging during this developmental period, and the large-scale multi-site efforts which ultimately led to the explosion of interest in the field today. Lastly, we consider the growing pains of the community and the need for an academic society that bridges expertise in developmental neuroscience, clinical science, as well as computational and biomedical engineering, to ensure special consideration of the vulnerable mother-offspring dyad (especially during pregnancy), data quality, and image processing tools that are created, rather than adapted, for the young brain.
  • Deep Approaches to Learning, Student Satisfaction, and Employability in STEM
    Kapania, Madhu; Savla, Jyoti S.; Skaggs, Gary (MDPI, 2025-08-29)
    This study examines the link between deep approaches to learning (DAL) and undergraduate senior students’ employability skills and perceived satisfaction in STEM fields in the United States. DAL, comprising higher-order (HO) and reflective/integrated (RI) learning constructs, enhances the understanding of real-world applications and promotes reflective thinking about individual ideas in broader contexts. HO activities focus on analyzing, synthesizing, and applying new information in practical scenarios such as internships, classroom discussions, and presentations. RI activities involve integrating existing knowledge with new ideas. The efficacy of DAL in improving student outcomes including employability and satisfaction skills was investigated using Structural Equation Modeling (SEM), which included a Confirmatory Factor Analysis (CFA) to measure observed variables associated with the four latent factors (HO, RI, student satisfaction, and employability skills), followed by structural analysis to explore the relationship between these latent factors. Data from 14,292 senior students surveyed by the National Study of Student Engagement (NSSE) in 2018 were analyzed. The results indicated a significant positive effect of DAL on students’ satisfaction and perceived employability skills, underscoring its importance in higher education for STEM students. These findings can guide higher education institutions (HEIs) in focusing on DAL activities for meaningful learning outcomes and enhanced critical thinking.
  • Long-Term Effects of Adverse Maternal Care on Hypothalamic–Pituitary–Adrenal (HPA) Axis Function of Juvenile and Adolescent Macaques
    McCormack, Kai; Bramlett, Sara; Morin, Elyse L.; Siebert, Erin R.; Guzman, Dora; Howell, Brittany; Sanchez, Mar M. (MDPI, 2025-02-15)
    Early life adversity (ELA) is a known risk factor for psychopathology, including stress-related anxiety and depressive disorders. The underlying mechanisms and developmental changes remain poorly understood. A likely underpinning is the impact of ELA on the development of stress response systems, including the hypothalamic–pituitary–adrenal (HPA) axis. Our group studied a translational ELA model of spontaneous infant maltreatment by the mother in rhesus macaques, where we used a cross-fostering design to randomly assign infant macaques to either Control or Maltreating (MALT) foster mothers at birth to examine the impact of adverse caregiving on the development of the HPA axis, while controlling for the confounding effects of heritable and prenatal factors. We previously reported higher levels of plasma and hair cortisol (CORT) across the first 6 postnatal months (equivalent to the first 2 years of life in humans) in the MALT than in the Control infants. Here, we followed the same cohort of infants longitudinally to assess the long-term developmental impact of this adverse experience on HPA axis function during the juvenile (12, 18 months) and late adolescent (~5 years) periods. For this, we collected measurements of diurnal CORT rhythm and glucocorticoid negative feedback using the dexamethasone suppression test (DST). At 12 months, we found higher diurnal CORT secretion in MALT females compared to Control females, and impaired negative feedback in response to the DST in both sexes in the MALT group. However, ELA group differences in the HPA axis function disappeared by 18 months and late adolescence, while sex differences in diurnal CORT rhythm emerged or became stronger. These results suggest that infant maltreatment causes dysregulation of the HPA axis during the first year of life, with HPA axis function normalizing later, during the pre-pubertal juvenile period and adolescence. This suggests that the impact of maltreatment on HPA axis function may be transient, at least if the adverse experience stops. Our findings are consistent with human evidence of recalibration/normalization of HPA axis function during adolescence in children that switch from adverse/deprived environments to supportive adoptive families. This research has broad implications regarding the biological processes that translate ELA to psychopathology during development and the pathways to resiliency.
  • Evaluation of Interactive Demonstration in Voice-assisted Counting for Young Children
    Karunaratna, Sulakna; Vargas-Diaz, Daniel; Kim, Jisun; Wang, Jenny; Choi, Koeun; Lee, Sang Won (ACM, 2024-11-11)
    In recent years, the number of AI voice agent applications designed to help young children learn math has increased. However, the impact of interactivity within these applications on children’s learning and engagement remains unexplored. While current apps may employ various levels of interactions, such as visual, haptic, sound, and animation, the efficacy of these interactions in facilitating children’s learning remains uncertain. This research investigates how varying levels of interactivity in touch-based interfaces, combined with an AI voice agent, affect the learning of counting skills in children aged 2 to 4 years.We examine three conditions: baseline (no demonstration), animated demonstration, and interactive demonstration. By examining how these different levels of interactivity influence children’s engagement with math apps, this study seeks to enhance our understanding of effective design strategies for educational technology targeting early childhood education. The findings of this research hold the potential to inform the development of interfaces for math games that leverage both touch-based interactions and AI voice assistants to support young children’s learning of foundational mathematical concepts.
  • Associations between maternal personality dysfunction and emotion suppression and adolescent emotion suppression
    Phillips, Jennifer J.; Smith, Cynthia L.; Bell, Martha A. (2024-11-27)
    Background: Adaptive strategies of emotion regulation are important for adolescents, as maladaptive strategies of such can manifest as psychopathology that is sometimes severe. Individual biological characteristics and influences from peers have been shown to have an effect on the development of emotion regulation strategies in adolescents. Maternal factors, however, have received less attention in this age group regarding how they might predict emotion regulation in adolescents. Given that prior work has demonstrated that certain maternal factors, like emotion regulation and personality, play a crucial role in the development of emotion regulation strategies in early childhood, we sought to examine these associations in adolescents in our current study. Methods: Adolescents and their mothers (n = 123) both self-reported data on their own emotion regulation, and mothers also self-reported data on their own personality dysfunction. We operationalized maternal and adolescent emotion regulation as emotion suppression, a maladaptive emotion regulation strategy that is commonly used by adolescents. Results: Our data demonstrated that both maternal emotion suppression and interpersonal personality dysfunction were positively associated with adolescent emotion suppression. No associations among maternal intrapersonal personality functioning and adolescent emotion suppression were detected. Conclusions: Maternal personality dysfunction and emotion suppression both independently predicted adolescent emotion suppression use. These results support the idea that maternal characteristics play a role in shaping emotion regulation in adolescence.
  • Evaluating attachment-based family therapy in residential treatment in the United States: does adolescents’ increased attachment security to caregivers lead to decreases in depressive symptoms?
    Diamond, Guy; Rivers, Alannah S.; Winston-Lindeboom, Payne; Russon, Jody M.; Roeske, Michael (2024-11-13)
    Background: The inclusion of family therapy in residential treatment centers (RTCs) has increased over time. However, there is little data on whether empirically-supported family therapies (ESFTs) are being adopted and if they contribute to treatment effectiveness. This study aimed to test whether Attachment-Based Family Therapy (ABFT), an ESFT integrated into a large residential psychiatric system, would improve perceived attachment insecurity (anxiety and avoidance) and contribute to decreases in depression for adolescents. Method: ABFT was integrated into the clinical program of a large, residential psychiatric system. All family therapists were trained to a level of certification. Improvement was measured by changes in adolescent’s perceived attachment to caregivers and reduction in depressive symptoms. The sample included 4786 patients. Attachment insecurity and depressive symptoms were measured at intake, week 3, and week 5. A random-intercept, cross-lagged panel model was used to examine the relationships between attachment and depression over time. Results: The results generally supported hypotheses. Attachment insecurity and depressive symptoms improved over the five weeks of treatment. Improvements in attachment avoidance preceded improvements in depressive symptoms within subjects, over time. Simultaneously, improvements in depressive symptoms preceded those in both dimensions of attachment. Thus, improvement in perceived attachment was associated with a reduction in depressive symptoms. Conclusion: RTCs that can generate improvements in attachment insecurity and depressive symptoms, via ABFT or other ESFTs, might improve treatment outcomes, and ideally, adolescents’ successful transition back home to families. More research is needed to disentangle the contribution of ABFT and other treatment elements in a multimodal, residential treatment program. The study supports the call for increased incorporation of families into the RTC treatment process.
  • Young Children’s Directed Question Asking in Preschool Classrooms
    Wong, Michelle; Choi, Koeun; Barak, Libby; Lapidow, Elizabeth; Austin, Jennifer; Shafto, Patrick; Bonawitz, Elizabeth (MDPI, 2024-08-27)
    Question asking is a prevalent aspect of children’s speech, providing a means by which young learners can rapidly gain information about the world. Previous research has demonstrated that children exhibit sensitivity to the knowledge state of potential informants in laboratory settings. However, it remains unclear whether and how young children are inclined to direct questions that support learning deeper content to more knowledgeable informants in naturalistic classroom contexts. In this study, we examined children’s question-asking targets (adults, other preschoolers, self-talk) during an open-play period in a US preschool classroom and assessed how the cognitive and linguistic characteristics of questions varied as a function of the intended recipient. Further, we examined how these patterns changed with age. We recorded the spontaneous speech of individual children between the ages of 3 and 6 years (N = 30, totaling 2875 utterances) in 40-min open-period sessions in their preschool day, noting whether the speech was directed toward an adult, another child, or was stated to self. We publish this fully transcribed database with contextual and linguistic details coded as open access to all future researchers. We found that questions accounted for a greater proportion of preschoolers’ adult-directed speech than of their child-directed and self-directed speech, with a particular increase in questions that supported broader learning goals when directed to an adult. Younger children directed a higher proportion of learning questions to adults than themselves, whereas older children asked similar proportions of questions to both, suggesting a difference in younger and older children’s question-asking strategies. Although children used greater lexical diversity in questions than in other utterances, their question formulation in terms of length and diversity remained consistent across age and recipient types, reflecting their general linguistic abilities. Our findings reveal that children discriminately choose “what” and “whom” to ask in daily spontaneous conversations. Even in less-structured school contexts, preschoolers direct questions to the informant most likely to be able to provide an adequate answer.
  • Bridging the Gap: Early Education on Robot and AI Ethics through the Robot Theater Platform in an Informal Learning Environment
    Mitchell, Jennifer; Dong, Jiayuan; Yu, Shuqi; Harmon, Madison; Holstein, Alethia; Shim, Joon Hyun; Choi, Koeun; Zhu, Qin; Jeon, Myounghoon (ACM, 2024-03-11)
    With the rapid advancement of robotics and AI, educating the next generation on ethical coexistence with these technologies is crucial. Our research explored the potential of a child-robot theater afterschool program in introducing and discussing robot and AI ethics with elementary school children. Conducted with 30 participants from a socioeconomically underprivileged school, the program blended STEM (Science, Technology, Engineering & Mathematics) with the arts, focusing on ethical issues in robotics and AI. Using interactive scenarios and a theatrical performance, the program aimed to enhance children’s understanding of major ethical issues in robotics and AI, such as bias, transparency, privacy, usage, and responsibility. Preliminary findings indicate the program’s success in engaging children in meaningful ethical discussions, demonstrating the potential of innovative, interactive educational methods in early education. This study contributes significantly to integrating ethical robotics and AI in early learning, preparing young minds for a technologically advanced and socially responsible future.
  • Risk of Excess Maternal Folic Acid Supplementation in Offspring
    Xu, Xiguang; Zhang, Ziyu; Lin, Yu; Xie, Hehuang (MDPI, 2024-03-06)
    Folate, also known as vitamin B9, facilitates the transfer of methyl groups among molecules, which is crucial for amino acid metabolism and nucleotide synthesis. Adequate maternal folate supplementation has been widely acknowledged for its pivotal role in promoting cell proliferation and preventing neural tube defects. However, in the post-fortification era, there has been a rising concern regarding an excess maternal intake of folic acid (FA), the synthetic form of folate. In this review, we focused on recent advancements in understanding the influence of excess maternal FA intake on offspring. For human studies, we summarized findings from clinical trials investigating the effects of periconceptional FA intake on neurodevelopment and molecular-level changes in offspring. For studies using mouse models, we compiled the impact of high maternal FA supplementation on gene expression and behavioral changes in offspring. In summary, excessive maternal folate intake could potentially have adverse effects on offspring. Overall, we highlighted concerns regarding elevated maternal folate status in the population, providing a comprehensive perspective on the potential adverse effects of excessive maternal FA supplementation on offspring.