Very few academic programs in pre-service teacher education include opportunities for current and future K-12 educators to develop the necessary skills to teach in an online setting. While limited research has been done related to the preparation of teachers for online instruction, the evidence-based best practices in the field of instructional design and technology can inform graduate curriculum development in this area. This chapter presents a current review of academic programming and trends related to preparing K-12 educators to be effective teachers in online and blended learning environments. Additionally, essential skills and knowledge for teaching online in the K-12 context will be explored and recommendations made for curricular planning to meet these necessary competencies.