The system will be unavailable due to maintenance on Thursday July 19 from 7:00-8:30 am ET.
Supramolecular complexes as photoactivated DNA cleavage agents
Brewer, Karen J.
MetadataShow full item record
The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal (e.g. Rh) via a bridging π-acceptor ligand. A bioactive metal-to-metal charge transfer state capable of cleaving DNA is thus generated. The complexes function when irradiated with low energy visible light with or without molecular oxygen.
Virginia Tech Intellectual Properties, Inc.
- Virginia Tech Patents