Destination Areas provide faculty and students with new tools to identify and solve complex, 21st-century problems in which Virginia Tech already has significant strengths and can take a global leadership role. The initiative represents the next step in the evolution of the land-grant university to meet economic and societal needs of the world. DAs connect the full span of relevant knowledge necessary for addressing issues comprehensively. Humanistic, scientific, and technological perspectives are addressed in relationship to one another and they are treated as complementary to overcome traditional academic boundaries, such as those that separate the STEM fields and liberal arts. [http://provost.vt.edu/destination-areas.html]

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Recent Submissions

  • A Pilot Study of the Effects of Mindfulness-Based Cognitive Therapy on Positive Affect and Social Anxiety Symptoms 

    Strege, Marlene V.; Swain, Deanna; Bochicchio, Lauren; Valdespino, Andrew; Richey, John A. (Frontiers, 2018-06-01)
    Randomized controlled trials have demonstrated that mindfulness-based cognitive therapy (MBCT) is efficacious in reducing residual depressive symptoms and preventing future depressive episodes (Kuyken et al., 2016). One ...
  • Drought and Human Impacts on Land Use and Land Cover Change in a Vietnamese Coastal Area 

    Tran, Hoa Thi; Campbell, James B.; Wynne, Randolph H.; Shao, Yang; Phan, Son Viet (MDPI, 2019-02-08)
    Drought is a dry-weather event characterized by a deficit of water resources in a period of year due to less rainfall than normal or overexploitation. This insidious hazard tends to occur frequently and more intensively ...
  • Effects of Producer and Transmission Reliability on the Sustainability Assessment of Power System Networks 

    Vargas-Jaramillo, Jose R.; Montanez-Barrera, Jhon A.; von Spakovsky, Michael R.; Mili, Lamine; Cano-Andrade, Sergio (MDPI, 2019-02-10)
    Details are presented of the development and incorporation of a generation and transmission reliability approach in an upper-level sustainability assessment framework for power system planning. This application represents ...
  • IIHCC Newsletter, November 2018 

    Unknown author (Virginia Tech, 2018-11)
    IIHCC has identified better ways to improve communication, transparency, and engagement between IIHCC and those wishing to become or remain involved with the DA. A monthly newsletter is a great solution for disseminating ...
  • IIHCC Newsletter, December 2018 

    Unknown author (Virginia Tech, 2018-12)
    IIHCC has identified better ways to improve communication, transparency, and engagement between IIHCC and those wishing to become or remain involved with the DA. A monthly newsletter is a great solution for disseminating ...
  • IIHCC Newsletter – Winter Edition 2019 

    Unknown author (Virginia Tech, 2019-01)
    In this edition—and future editions—a new section called “Cluster Hire Spotlight,” which serves as a mechanism to support and increase transdisciplinary collaborations with IIHCC Cluster Hires and the Virginia Tech community. ...
  • Quantifying climate sensitivity and climate-driven change in North American amphibian communities 

    Miller, David A. W.; Grant, Evan H. Campbell; Muths, Erin; Amburgey, Staci M.; Adams, Michael J.; Joseph, Maxwell B.; Waddle, J. Hardin; Johnson, Pieter T. J.; Ryan, Maureen E.; Schmidt, Benedikt R.; Calhoun, Daniel L.; Davis, Courtney L.; Fisher, Robert N.; Green, David M.; Hossack, Blake R.; Rittenhouse, Tracy A. G.; Walls, Susan C.; Bailey, Larissa L.; Cruickshank, Sam S.; Fellers, Gary M.; Gorman, Thomas A.; Haas, Carola A.; Hughson, Ward; Pilliod, David S.; Price, Steven J.; Ray, Andrew M.; Sadinski, Walt; Saenz, Daniel; Barichivich, William J.; Brand, Adrianne; Brehme, Cheryl S.; Dagit, Rosi; Delaney, Katy S.; Glorioso, Brad M.; Kats, Lee B.; Kleeman, Patrick M.; Pearl, Christopher A.; Rochester, Carlton J.; Riley, Seth P. D.; Roth, Mark; Sigafus, Brent H. (2018-09-25)
    Changing climate will impact species' ranges only when environmental variability directly impacts the demography of local populations. However, measurement of demographic responses to climate change has largely been limited ...
  • Low-input and multiplexed microfluidic assay reveals epigenomic variation across cerebellum and prefrontal cortex 

    Ma, Sai; Hsieh, Yuan-Pang; Ma, Jian; Lu, Chang (AAAS, 2018-04-18)
    Extensive effort is under way to survey the epigenomic landscape of primary ex vivo tissues to establish normal reference data and to discern variation associated with disease. The low abundance of some tissue types and ...
  • Expression and activity of the urokinase plasminogen activator system in canine primary brain tumors 

    Rossmeisl, John H.; Hall-Manning, Kelli; King, Jamie N.; Davalos, Rafael V.; Debinski, Waldemar; Elankumaran, Subbiah (Dove Press, 2017-04-12)
    Background: The expression of the urokinase plasminogen activator receptor (uPAR), a glycosylphosphatidylinositol-anchored protein family member, and the activity of its ligand, urokinase-type plasminogen activator (uPA), ...
  • Canine Butterfly Glioblastomas: a Neuroradiological Review 

    Rossmeisl, John H.; Clapp, Kemba; Pancotto, Theresa E.; Emch, Samantha; Robertson, John L.; Debinski, Waldemar (Frontiers, 2016-05-19)
    In humans, high-grade gliomas may infiltrate across the corpus callosum resulting in bihemispheric lesions that may have symmetrical, winged-like appearances. This particular tumor manifestation has been coined a “butterfly” ...
  • High-Frequency Irreversible Electroporation for Intracranial Meningioma: A Feasibility Study in a Spontaneous Canine Tumor Model 

    Latouche, Eduardo L.; Arena, Christopher B.; Ivey, Jill W.; Garcia, Paulo A.; Pancotto, Theresa E.; Pavlisko, Noah; Verbidge, Scott S.; Davalos, Rafael V.; Rossmeisl, John H. (Sage, 2018)
    High-frequency irreversible electroporation is a nonthermal method of tissue ablation that uses bursts of 0.5- to 2.0-microsecond bipolar electric pulses to permeabilize cell membranes and induce cell death. High-frequency ...
  • Stream Vulnerability to Widespread and Emergent Stressors: A Focus on Unconventional Oil and Gas 

    Entrekin, Sally A.; Maloney, Kelly O.; Kapo, Katherine E.; Walters, Annika W.; Evans-White, Michelle A.; Klemow, Kenneth M. (PLOS, 2015-09-23)
    Multiple stressors threaten stream physical and biological quality, including elevated nutrients and other contaminants, riparian and in-stream habitat degradation and altered natural flow regime. Unconventional oil and ...
  • Do biofilm communities respond to the chemical signatures of fracking? A test involving streams in North-central Arkansas 

    Johnson, Wilson H.; Douglas, Marlis R.; Lewis, Jeffrey A.; Stuecker, Tara N.; Carbonero, Franck G.; Austin, Bradley, J.; Evans-White, Michelle A.; Entrekin, Sally A.; Douglas, Michael E. (BMC, 2017)
    Background: Unconventional natural gas (UNG) extraction (fracking) is ongoing in 29 North American shale basins (20 states), with ~6000 wells found within the Fayetteville shale (north-central Arkansas). If the chemical ...
  • Global patterns and drivers of ecosystem functioning in rivers and riparian zones 

    Tiegs, Scott D.; Entrekin, Sally; et al (American Association for the Advancement of Science, 2019-01-09)
    River ecosystems receive and process vast quantities of terrestrial organic carbon, the fate of which depends strongly on microbial activity. Variation in and controls of processing rates, however, are poorly characterized ...
  • City-Wide Eco-Routing Navigation Considering Vehicular Communication Impacts 

    Elbery, Ahmed; Rakha, Hesham (MDPI, 2019-01-12)
    Intelligent Transportation Systems (ITSs) utilize Vehicular Ad-hoc Networks (VANETs) to collect, disseminate, and share data with the Traffic Management Center (TMC) and different actuators. Consequently, packet drop and ...
  • Use of Electroencephalography (EEG) for the Analysis of Emotional Perception and Fear to Nightscapes 

    Kim, Mintai; Cheon, SangHyun; Kang, Youngeun (MDPI, 2019-01-04)
    As the necessity for safety and aesthetic of nightscape have arisen, the importance of nightscapes (i.e., nighttime landscape) planning has garnered the attention of mainstream consciousness. Therefore, this study was to ...
  • Mechanistic insights into the effect of humidity on airborne influenza virus survival, transmission and incidence 

    Marr, Linsey C.; Tang, Julian W.; Van Mullekom, Jennifer; Lakdawala, Seema S. (Royal Society Publishing, 2019-01-16)
    Influenza incidence and seasonality, along with virus survival and transmission, appear to depend at least partly on humidity, and recent studies have suggested that absolute humidity (AH) is more important than relative ...
  • Antimicrobial Resistance Prediction in PATRIC and RAST 

    Davis, James J.; Boisvert, Sebastien; Brettin, Thomas; Kenyon, Ronald W.; Mao, Chunhong; Olson, Robert; Overbeek, Ross; Santerre, John; Shukla, Maulik; Wattam, Alice R.; Will, Rebecca; Xia, Fangfang; Stevens, Rick (Springer Nature, 2016-06-14)
    The emergence and spread of antimicrobial resistance (AMR) mechanisms in bacterial pathogens, coupled with the dwindling number of effective antibiotics, has created a global health crisis. Being able to identify the genetic ...
  • BDNF Val(66)Met Polymorphism Influences Visuomotor Associative Learning and the Sensitivity to Action Observation 

    Taschereau-Dumouchel, Vincent; Hetu, Sebastien; Michon, Pierre-Emmanuel; Vachon-Presseau, Etienne; Massicotte, Elsa; De Beaumont, Louis; Fecteau, Shirley; Poirier, Judes; Mercier, Catherine; Chagnon, Yvon C.; Jackson, Philip L. (Springer Nature, 2016-10-05)
    Motor representations in the human mirror neuron system are tuned to respond to specific observed actions. This ability is widely believed to be influenced by genetic factors, but no study has reported a genetic variant ...

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