Odor-Specific Daily Rhythms in the Olfactory Sensitivity and Behavior of Aedes aegypti Mosquitoes

dc.contributor.authorEilerts, Diane F.en
dc.contributor.authorVanderGiessen, Morgenen
dc.contributor.authorBose, Elizabeth A.en
dc.contributor.authorBroxton, Kyeraen
dc.contributor.authorVinauger, Clémenten
dc.contributor.departmentBiochemistryen
dc.date.accessioned2018-10-31T17:01:08Zen
dc.date.available2018-10-31T17:01:08Zen
dc.date.issued2018-10-23en
dc.date.updated2018-10-31T15:28:23Zen
dc.description.abstractMany biological processes and behaviors in mosquitoes display rhythmic patterns, allowing for fine tuning to cyclic environmental conditions. In mosquitoes, vector-host interactions are primarily mediated by olfactory signals. Previous studies have established that, in the malaria vector <i>Anopheles gambiae</i>, rhythmic expression of odorant binding proteins and takeout proteins in the antenna resulted in a corresponding rhythm in olfactory sensitivity to relevant host odors. However, it remained unclear how rhythms observed in olfactory sensitivity affect or explain rhythms in behavioral output, which ultimately impacts disease transmission. In order to address this knowledge gap, we quantified and compared patterns in locomotor activity, olfactory sensitivity, and olfactory behaviors in adult female <i>Aedes aegypti</i> mosquitoes. Here, we demonstrate an odorant-specific modulation of olfactory sensitivity in <i>Ae. aegypti</i>, decoupled from rhythms in olfactory behavior. Additionally, behavioral assays performed herein represent the first evidence of a time-dependence of the olfactory activation of behavior in <i>Ae. aegypti</i> mosquitoes. Results suggest that olfactory behavior of <i>Aedes</i> mosquitoes is modulated at both the peripheral (antenna) and central levels. As such, this work serves as a foundation for future studies aimed at further understanding the neural and molecular mechanisms underlying behavioral plasticity.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationEilerts, D.F.; VanderGiessen, M.; Bose, E.A.; Broxton, K.; Vinauger, C. Odor-Specific Daily Rhythms in the Olfactory Sensitivity and Behavior of Aedes aegypti Mosquitoes. Insects 2018, 9, 147.en
dc.identifier.doihttps://doi.org/10.3390/insects9040147en
dc.identifier.urihttp://hdl.handle.net/10919/85612en
dc.language.isoenen
dc.publisherMDPIen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectdaily rhythmsen
dc.subjectbiological rhythmsen
dc.subjectmosquitoesen
dc.subjectvectorsen
dc.subjectolfactionen
dc.subjectelectrophysiologyen
dc.subjectbehavioren
dc.titleOdor-Specific Daily Rhythms in the Olfactory Sensitivity and Behavior of Aedes aegypti Mosquitoesen
dc.title.serialInsectsen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
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