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Chemokines and Chemokine Receptors in the Development of Lupus Nephritis

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dc.contributor.authorLiao, Xiaofengen
dc.contributor.authorPirapakaran, Tharshikhaen
dc.contributor.authorLuo, Xin M.en
dc.date.accessioned2017-09-18T09:35:37Zen
dc.date.available2017-09-18T09:35:37Zen
dc.date.issued2016-06-14en
dc.date.updated2017-09-18T09:35:37Zen
dc.description.abstractLupus nephritis (LN) is a major cause of morbidity and mortality in the patients with systemic lupus erythematosus (SLE), an autoimmune disease with damage to multiple organs. Leukocyte recruitment into the inflamed kidney is a critical step to promote LN progression, and the chemokine/chemokine receptor system is necessary for leukocyte recruitment. In this review, we summarize recent studies on the roles of chemokines and chemokine receptors in the development of LN and discuss the potential and hurdles of developing novel, chemokine-based drugs to treat LN.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationXiaofeng Liao, Tharshikha Pirapakaran, and Xin M. Luo, “Chemokines and Chemokine Receptors in the Development of Lupus Nephritis,” Mediators of Inflammation, vol. 2016, Article ID 6012715, 15 pages, 2016. doi:10.1155/2016/6012715en
dc.identifier.doihttps://doi.org/10.1155/2016/6012715en
dc.identifier.urihttp://hdl.handle.net/10919/78933en
dc.language.isoenen
dc.publisherHindawien
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.holderCopyright © 2016 Xiaofeng Liao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.titleChemokines and Chemokine Receptors in the Development of Lupus Nephritisen
dc.title.serialMediators of Inflammationen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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