Determining the role of natural SARS-CoV-2 infection in the death of domestic pets: 10 cases (2020-2021)

dc.contributor.authorCarpenter, Annen
dc.contributor.authorGhai, Ria R.en
dc.contributor.authorGary, Joyen
dc.contributor.authorRitter, Jana M.en
dc.contributor.authorCarvallo, Francisco R.en
dc.contributor.authorDiel, Diego G.en
dc.contributor.authorMartins, Mathiasen
dc.contributor.authorMurphy, Juliaen
dc.contributor.authorSchroeder, Betsy A.en
dc.contributor.authorBrightbill, Kevinen
dc.contributor.authorTewari, Deepankeren
dc.contributor.authorBoger, Loreen
dc.contributor.authorGabel, Julieen
dc.contributor.authorCobb, Roberten
dc.contributor.authorHennebelle, Janemarieen
dc.contributor.authorStanton, James B.en
dc.contributor.authorMcCullough, Kathrynen
dc.contributor.authorMosley, Yung-Yi C.en
dc.contributor.authorNaikare, Hemant K.en
dc.contributor.authorRadcliffe, Rachelen
dc.contributor.authorParr, Boyden
dc.contributor.authorBalsamo, Garyen
dc.contributor.authorRobbins, Brenten
dc.contributor.authorSmith, Daviden
dc.contributor.authorSlavinski, Sallyen
dc.contributor.authorWilliams, Carlen
dc.contributor.authorMeckes, Dougen
dc.contributor.authorJones, Deeen
dc.contributor.authorFrazier, Tonyen
dc.contributor.authorSteury, Kelleyen
dc.contributor.authorRooney, Janeen
dc.contributor.authorTorchetti, Miaen
dc.contributor.authorWendling, Natalieen
dc.contributor.authorCurrie, Dustinen
dc.contributor.authorBehravesh, Casey Bartonen
dc.contributor.authorWallace, Ryan M.en
dc.date.accessioned2021-11-08T19:34:57Zen
dc.date.available2021-11-08T19:34:57Zen
dc.date.issued2021-11-01en
dc.description.abstractOBJECTIVE To establish a pathoepidemiological model to evaluate the role of SARS-CoV-2 infection in the first 10 companion animals that died while infected with SARS-CoV-2 in the US. ANIMALS 10 cats and dogs that tested positive for SARS-CoV-2 and died or were euthanized in the US between March 2020 and January 2021. PROCEDURES A standardized algorithm was developed to direct case investigations, determine the necessity of certain diagnostic procedures, and evaluate the role, if any, that SARS-CoV-2 infection played in the animals' course of disease and death. Using clinical and diagnostic information collected by state animal health officials, state public health veterinarians, and other state and local partners, this algorithm was applied to each animal case. RESULTS SARS-CoV-2 was an incidental finding in 8 animals, was suspected to have contributed to the severity of clinical signs leading to euthanasia in 1 dog, and was the primary reason for death for 1 cat. CONCLUSIONS AND CLINICAL RELEVANCE This report provides the global community with a standardized process for directing case investigations, determining the necessity of certain diagnostic procedures, and determining the clinical significance of SARS-CoV-2 infections in animals with fatal outcomes and provides evidence that SARS-CoV-2 can, in rare circumstances, cause or contribute to death in pets.en
dc.description.adminPublic domain – authored by a U.S. government employeeen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.2460/javma.259.9.1032en
dc.identifier.eissn1943-569Xen
dc.identifier.issn0003-1488en
dc.identifier.issue9en
dc.identifier.pmid34647475en
dc.identifier.urihttp://hdl.handle.net/10919/106547en
dc.identifier.volume259en
dc.language.isoenen
dc.rightsPublic Domain (U.S.)en
dc.rights.urihttp://creativecommons.org/publicdomain/mark/1.0/en
dc.titleDetermining the role of natural SARS-CoV-2 infection in the death of domestic pets: 10 cases (2020-2021)en
dc.title.serialJAVMA-Journal of the American Veterinary Medical Associationen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
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