Glycosphingolipids in Cardiovascular Disease: Insights from Molecular Mechanisms and Heart Failure Models

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dc.contributor.authorHuang, Sarahen
dc.contributor.authorAbutaleb, Karimaen
dc.contributor.authorMishra, Sumitaen
dc.date.accessioned2024-10-25T13:55:30Zen
dc.date.available2024-10-25T13:55:30Zen
dc.date.issued2024-10-08en
dc.date.updated2024-10-25T13:42:34Zen
dc.description.abstractThis review explores the crucial role of glycosphingolipids (GSLs) in the context of cardiovascular diseases (CVDs), focusing on their biosynthesis, metabolic pathways, and implications for clinical outcomes. GSLs are pivotal in regulating a myriad of cellular functions that are essential for heart health and disease progression. Highlighting findings from both human cohorts and animal models, this review emphasizes the potential of GSLs as biomarkers and therapeutic targets. We advocate for more detailed mechanistic studies to deepen our understanding of GSL functions in cardiovascular health, which could lead to innovative strategies for diagnosis, treatment, and personalized medicine in cardiovascular care.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationHuang, S.; Abutaleb, K.; Mishra, S. Glycosphingolipids in Cardiovascular Disease: Insights from Molecular Mechanisms and Heart Failure Models. Biomolecules 2024, 14, 1265.en
dc.identifier.doihttps://doi.org/10.3390/biom14101265en
dc.identifier.urihttps://hdl.handle.net/10919/121393en
dc.language.isoenen
dc.publisherMDPIen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectglycosphingolipidsen
dc.subjectheart failureen
dc.subjectHFrEFen
dc.subjectHFpEFen
dc.subjectceramideen
dc.titleGlycosphingolipids in Cardiovascular Disease: Insights from Molecular Mechanisms and Heart Failure Modelsen
dc.title.serialBiomoleculesen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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Journal Articles, Multidisciplinary Digital Publishing Institute (MDPI)
Scholarly Works, Fralin Biomedical Research Institute at VTC
Scholarly Works, Human Nutrition, Foods, and Exercise
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