Metastatic Plasmacytoid Urothelial Carcinoma Masquerading as a Primary Signet Ring Cell Carcinoma of the Duodenum

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dc.contributor.authorMir, Adil S.en
dc.contributor.authorMouchli, Mohamaden
dc.contributor.authorLebel, David P.en
dc.contributor.authorGrider, Douglas J.en
dc.date.accessioned2024-01-23T12:55:23Zen
dc.date.available2024-01-23T12:55:23Zen
dc.date.issued2023-08en
dc.description.abstractPlasmacytoid urothelial carcinoma can histologically mimic gastrointestinal signet ring cell carcinoma, a potential diagnostic pitfall resulting in improper clinical management. We present a rare case of a malignant duodenal ulcer due to metastasis from plasmacytoid urothelial carcinoma. Only by histological and retrospective immunohistochemical comparison with the primary bladder tumor was this revealed as a metastasis from a plasmacytoid urothelial carcinoma. This case report highlights the importance of clinical correlation and comparison with any previous pathology specimens, the limitations of immunohistochemical staining, and the utilization of both old and new immunohistochemical tools when differentiating signet ring cell carcinomas of primary sites versus potential metastases.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.7759/cureus.44454en
dc.identifier.eissn2168-8184en
dc.identifier.issn2168-8184en
dc.identifier.issue8en
dc.identifier.orcidGrider, Douglas [0000-0002-6346-094X]en
dc.identifier.otherPMC10544159en
dc.identifier.pmid37791187en
dc.identifier.urihttps://hdl.handle.net/10919/117587en
dc.identifier.volume15en
dc.language.isoenen
dc.publisherSpringeren
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pubmed/37791187en
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectcd-138en
dc.subjectpitfallen
dc.subjectplasmacytoiden
dc.subjectrare cancersen
dc.subjectsmall bowel malignancyen
dc.subjecturothelial malignancyen
dc.titleMetastatic Plasmacytoid Urothelial Carcinoma Masquerading as a Primary Signet Ring Cell Carcinoma of the Duodenumen
dc.title.serialCureusen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherCase Reportsen
dc.type.othercase-reporten
dcterms.dateAccepted2023-08-31en
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicineen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicine/Basic Scienceen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicine/Basic Science/Basic Scienceen

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