Live attenuated chimeric porcine circovirus vaccine

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dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.en
dc.contributor.inventorMeng, Xiang-Jinen
dc.contributor.inventorBeach, Nathan M.en
dc.contributor.inventorRamamoorthy, Sheelaen
dc.date.accessed2019-02-15en
dc.date.accessioned2019-02-26T22:23:54Zen
dc.date.available2019-02-26T22:23:54Zen
dc.date.filed2014-02-06en
dc.date.issued2017-04-04en
dc.description.abstractThe present invention provides a novel chimeric porcine circovirus infectious DNA clone and live attenuated chimeric virus with the PCV2, preferably of subtype PCV2b, capsid gene integrated into a non-pathogenic PCV1 virus genome. In a particular embodiment, the PCV2 capids gene is of subtype PCV2b, the predominant subtype circulating in pigs worldwide. The attenuated chimeric virus, designated PCV1-2b, effectively protects pigs from PCV2b challenges, and can be used as a live vaccine, as well as an inactivated (killed) vaccine, that provides protection and cross protection against PCV2b and PCV2a subtypes infection. The live attenuated vaccine of the present invention is also effective protecting pigs from porcine circovirus-associated disease (PCVAD).en
dc.format.mimetypeapplication/pdfen
dc.identifier.applicationnumber14174635en
dc.identifier.patentnumber9610344en
dc.identifier.urihttp://hdl.handle.net/10919/87804en
dc.identifier.urlhttp://pimg-fpiw.uspto.gov/fdd/44/103/096/0.pdfen
dc.language.isoenen
dc.publisherUnited States Patent and Trademark Officeen
dc.subject.cpcA61K39/12en
dc.subject.cpcA61K2039/5252en
dc.subject.cpcA61K2039/5254en
dc.subject.cpcA61K2039/545en
dc.subject.cpcA61K2039/552en
dc.subject.cpcA61K2039/575en
dc.subject.cpcA61K2039/70en
dc.subject.cpcC12N7/00en
dc.subject.cpcC12N2750/10021en
dc.subject.cpcC12N2750/10022en
dc.subject.cpcC12N2750/10034en
dc.subject.cpcC12N2750/10051en
dc.subject.cpcC12N2750/10062en
dc.titleLive attenuated chimeric porcine circovirus vaccineen
dc.typePatenten
dc.type.dcmitypeTexten
dc.type.patenttypeutilityen

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Scholarly Works, Biomedical Sciences and Pathobiology
Scholarly Works, Virginia-Maryland College of Veterinary Medicine