Burden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015: findings from the Global Burden of Disease 2015 study

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dc.contributor.authorMokdad, Ali H.en
dc.contributor.authorMoradi-Lakeh, Maziaren
dc.contributor.authorEl Bcheraoui, Charbelen
dc.contributor.authorCharara, Raghiden
dc.contributor.authorKhalil, Ibrahimen
dc.contributor.authorAfshin, Ashkanen
dc.contributor.authorKassebaum, Nicholas J.en
dc.contributor.authorCollison, Michaelen
dc.contributor.authorDaoud, Farahen
dc.contributor.authorChew, Adrienneen
dc.contributor.authorKrohn, Kristopher J.en
dc.contributor.authorColombara, Dannyen
dc.contributor.authorEhrenkranz, Rebeccaen
dc.contributor.authorForeman, Kyle J.en
dc.contributor.authorFrostad, Josephen
dc.contributor.authorGodwin, William W.en
dc.contributor.authorKutz, Michaelen
dc.contributor.authorRao, Puja C.en
dc.contributor.authorReiner, Roberten
dc.contributor.authorTroeger, Christopheren
dc.contributor.authorWang, Haidongen
dc.contributor.authorAbajobir, Amanuel Alemuen
dc.contributor.authorAbbas, Kaja M.en
dc.contributor.authorAbera, Semaw Feredeen
dc.contributor.authorAbu-Raddad, Laith J.en
dc.contributor.authorAdane, Kelemeworken
dc.contributor.authorKiadaliri, Aliasghar Ahmaden
dc.contributor.authorAhmadi, Alirezaen
dc.contributor.authorBeshir, Muktaren
dc.contributor.authorAl-Eyadhy, Aymanen
dc.contributor.authorAlam, Khurshiden
dc.contributor.authorAlam, Nooreen
dc.contributor.authorAlasfoor, Deenaen
dc.contributor.authorAlizadeh-Navaei, Rezaen
dc.contributor.authorAl-Maskari, Fatmaen
dc.contributor.authorAl-Raddadi, Rajaaen
dc.contributor.authorAlsharif, Ubaien
dc.contributor.authorAltirkawi, Khalid A.en
dc.contributor.authorAnber, Nahlaen
dc.contributor.authorAnsari, Hosseinen
dc.contributor.authorAntonio, Carl Abelardo T.en
dc.contributor.authorAnwari, Palwashaen
dc.contributor.authorAsayesh, Hamiden
dc.contributor.authorAsgedom, Solomon Weldegebrealen
dc.contributor.authorAtey, Tesfay Meharien
dc.contributor.authorArthur, Euripide Frinel G.en
dc.contributor.authorBacha, Umaren
dc.contributor.authorBarac, Aleksandraen
dc.contributor.authorBazargan-Hejazi, Shahrzaden
dc.contributor.authorDrew, Charles R.en
dc.contributor.authorGeffen, Daviden
dc.contributor.authorBedi, Neerajen
dc.contributor.authorBhutta, Zulfiqar A.en
dc.contributor.authorMichael, Braueren
dc.contributor.authorButt, Zahid A.en
dc.contributor.authorCastaƱeda-Orjuela, Carlos A.en
dc.contributor.authorDanawi, Hadien
dc.contributor.authorDjalalinia, Shirinen
dc.contributor.authorEndries, Aman Yesufen
dc.contributor.authorEshrati, Babaken
dc.contributor.authorFarvid, Maryam S.en
dc.contributor.authorFereshtehnejad, Seyed-Mohammaden
dc.contributor.authorFischer, Florianen
dc.contributor.authorGarcia-Basteiro, Alberto L.en
dc.contributor.authorGebrehiwot, Kiros Tedlaen
dc.contributor.authorGebrehiwot, Tsegaye Teweldeen
dc.contributor.authorHailu, Gessessew Bugssaen
dc.contributor.authorHamadeh, Randah Ribhien
dc.contributor.authorHambisa, Mitiku Teshomeen
dc.contributor.authorHamidi, Sameren
dc.contributor.authorHassanvand, Mohammad Sadeghen
dc.contributor.authorHedayati, Mohammad T.en
dc.contributor.authorHorita, Nobuyukien
dc.contributor.authorHusseini, Abdullatifen
dc.contributor.authorSpencer, Lewis Jamesen
dc.contributor.authorJavanbakht, Mehdien
dc.contributor.authorJonas, Jost B.en
dc.contributor.authorKasaeian, Amiren
dc.contributor.authorKhader, Yousef Salehen
dc.contributor.authorKhan, Ejaz Ahmaden
dc.contributor.authorKhan, Gulfarazen
dc.contributor.authorKhoja, Abdullah Tawfih Abdullahen
dc.contributor.authorKhubchandani, Jagdishen
dc.contributor.authorKim, Yun Jinen
dc.contributor.authorKissoon, Niranjanen
dc.contributor.authorLarson, Heidi J.en
dc.contributor.authorLatif, Asma Abdulen
dc.contributor.authorLeshargie, Cheru Tesemaen
dc.contributor.authorLunevicius, Raimundasen
dc.contributor.authorAbd El Razek, Hassan Magdyen
dc.contributor.authorAbd El Razek, Mohammed Magdyen
dc.contributor.authorMajdzadeh, Rezaen
dc.contributor.authorMajeed, Azeemen
dc.contributor.authorMalekzadeh, Rezaen
dc.contributor.authorFarid, Habibolah Masoudien
dc.contributor.authorMehari, Alemen
dc.contributor.authorMemish, Ziad A.en
dc.contributor.authorMengistu, Desalegn Tadeseen
dc.contributor.authorMensah, George A.en
dc.contributor.authorMezgebe, Haftay Berhaneen
dc.contributor.authorNakamura, Sachikoen
dc.contributor.authorOren, Eyalen
dc.contributor.authorPourmalek, Farshaden
dc.contributor.authorQorbani, Mostafaen
dc.contributor.authorRadfar, Amiren
dc.contributor.authorRafay, Anwaren
dc.contributor.authorRahimi-Movaghar, Vafaen
dc.contributor.authorRai, Rajesh Kumaren
dc.contributor.authorRawaf, David Laithen
dc.contributor.authorRawaf, Salmanen
dc.contributor.authorRefaat, Amany H.en
dc.contributor.authorRezaei, Sataren
dc.contributor.authorRezai, Mohammad Sadeghen
dc.contributor.authorRoba, Hirbo Shoreen
dc.contributor.authorRoshandel, Gholamrezaen
dc.contributor.authorSafdarian, Mahdien
dc.contributor.authorSafiri, Saeiden
dc.contributor.authorSahraian, Mohammad Alien
dc.contributor.authorSalamati, Paymanen
dc.contributor.authorSamy, Abdallah M.en
dc.contributor.authorSartorius, Bennen
dc.contributor.authorSepanlou, Sadaf G.en
dc.contributor.authorShaikh, Masood Alien
dc.contributor.authorShamsizadeh, Mortezaen
dc.contributor.authorShigematsu, Mikaen
dc.contributor.authorSingh, Jasvinder A.en
dc.contributor.authorSufiyan, Muawiyyah Babaleen
dc.contributor.authorTehrani-Banihashemi, Arashen
dc.contributor.authorTemsah, Mohamad-Hanien
dc.contributor.authorTopor-Madry, Romanen
dc.contributor.authorUthman, Olalekan A.en
dc.contributor.authorVollset, Stein Emilen
dc.contributor.authorWakayo, Tolassaen
dc.contributor.authorWerdecker, Andreaen
dc.contributor.authorWijeratne, Tissaen
dc.contributor.authorYaghoubi, Mohsenen
dc.contributor.authorYimam, Hassen Hamiden
dc.contributor.authorYonemoto, Naohiroen
dc.contributor.authorYounis, Mustafa Z.en
dc.contributor.authorZaki, Maysaa El Sayeden
dc.contributor.authorJumaan, Aisha O.en
dc.contributor.authorVos, Theoen
dc.contributor.authorNaghavi, Mohsenen
dc.contributor.authorHay, Simon I.en
dc.contributor.authorMurray, Christopher J. L.en
dc.date.accessioned2019-09-06T13:59:19Zen
dc.date.available2019-09-06T13:59:19Zen
dc.date.issued2018-05en
dc.description.abstractWe used data from the Global Burden of Disease 2015 study (GBD) to calculate the burden of lower respiratory infections (LRIs) in the 22 countries of the Eastern Mediterranean Region (EMR) from 1990 to 2015. We conducted a systematic analysis of mortality and morbidity data for LRI and its specific etiologic factors, including pneumococcus, Haemophilus influenzae type b, Respiratory syncytial virus, and influenza virus. We used modeling methods to estimate incidence, deaths, and disability-adjusted life-years (DALYs). We calculated burden attributable to known risk factors for LRI. In 2015, LRIs were the fourth-leading cause of DALYs, causing 11,098,243 (95% UI 9,857,095-12,396,566) DALYs and 191,114 (95% UI 170,934-210,705) deaths. The LRI DALY rates were higher than global estimates in 2015. The highest and lowest age-standardized rates of DALYs were observed in Somalia and Lebanon, respectively. Undernutrition in childhood and ambient particulate matter air pollution in the elderly were the main risk factors. Our findings call for public health strategies to reduce the level of risk factors in each age group, especially vulnerable child and elderly populations.en
dc.description.notesDr. Carl Abelardo T. Antonio reports Grants and personal fees from Johnson and Johnson (Philippines), Inc. outside the submitted work. Dr. Jasvinder Singh serves as the principal investigator for an investigator-initiated study funded by Horizon Pharmaceuticals through a grant to DINORA, Inc., a 501 (c)(3) entity. Dr. Singh is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 36 companies; a member of the American College of Rheumatology's (ACR) Annual Meeting Planning Committee (AMPC); Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommittee; and a member of the Veterans Affairs Rheumatology Field Advisory Committee. Other authors have no conflict of interest.en
dc.description.sponsorshipHorizon Pharmaceuticals; American College of Rheumatology's (ACR) Annual Meeting Planning Committee (AMPC); Veterans Affairs Rheumatology Field Advisory Committee; Chair of the ACR Meet-the-Professor, Workshop and Study Group Subcommitteeen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1007/s00038-017-1007-0en
dc.identifier.eissn1661-8564en
dc.identifier.issn1661-8556en
dc.identifier.pmid28776246en
dc.identifier.urihttp://hdl.handle.net/10919/93495en
dc.identifier.volume63en
dc.language.isoenen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectLower respiratory infectionen
dc.subjectIncidenceen
dc.subjectMortalityen
dc.subjectDALYen
dc.subjectEastern Mediterranean Regionen
dc.titleBurden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015: findings from the Global Burden of Disease 2015 studyen
dc.title.serialInternational Journal of Public Healthen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.dcmitypeStillImageen

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