Genomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladesh

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dc.contributor.authorCarnegie, L.en
dc.contributor.authorMcCrone, J. T.en
dc.contributor.authordu Plessis, L.en
dc.contributor.authorHasan, M.en
dc.contributor.authorAli, M.Z.en
dc.contributor.authorBegum, R.en
dc.contributor.authorHassan, M.Z.en
dc.contributor.authorIslam, S.en
dc.contributor.authorRahman, M.H.en
dc.contributor.authorUddin, A.S.M.en
dc.contributor.authorSarker, M.S.en
dc.contributor.authorDas, T.en
dc.contributor.authorHossain, M.en
dc.contributor.authorKhan, M.en
dc.contributor.authorRazu, M.H.en
dc.contributor.authorAkram, A.en
dc.contributor.authorArina, S.en
dc.contributor.authorHoque, E.en
dc.contributor.authorMolla, M.M.A.en
dc.contributor.authorNafisaa, T.en
dc.contributor.authorAngra, P.en
dc.contributor.authorRambaut, A.en
dc.contributor.authorPullan, S.T.en
dc.contributor.authorOsman, K.L.en
dc.contributor.authorHoque, M.A.en
dc.contributor.authorBiswas, P.en
dc.contributor.authorFlora, M.S.en
dc.contributor.authorRaghwani, J.en
dc.contributor.authorFournié, G.en
dc.contributor.authorSamad, M.A.en
dc.contributor.authorHill, S.C.en
dc.date.accessioned2024-11-18T13:55:06Zen
dc.date.available2024-11-18T13:55:06Zen
dc.date.issued2024-11-13en
dc.date.updated2024-11-17T04:22:02Zen
dc.description.abstractBackground: Genomic epidemiology has helped reconstruct the global and regional movement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still a lack of understanding of SARS-CoV-2 spread in some of the world’s least developed countries (LDCs). Methods: To begin to address this disparity, we studied the transmission dynamics of the virus in Bangladesh during the country’s first COVID-19 wave by analysing case reports and whole-genome sequences from all eight divisions of the country. Results: We detected > 50 virus introductions to the country during the period, including during a period of national lockdown. Additionally, through discrete phylogeographic analyses, we identified that geographical distance and population -density and/or -size influenced virus spatial dispersal in Bangladesh. Conclusions: Overall, this study expands our knowledge of SARS-CoV-2 genomic epidemiology in Bangladesh, shedding light on crucial transmission characteristics within the country, while also acknowledging resemblances and differences to patterns observed in other nations.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationVirology Journal. 2024 Nov 13;21(1):291en
dc.identifier.doihttps://doi.org/10.1186/s12985-024-02560-2en
dc.identifier.urihttps://hdl.handle.net/10919/123624en
dc.language.isoenen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.holderThe Author(s)en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.titleGenomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladeshen
dc.title.serialVirology Journalen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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