Depression on cortical and subcortical dementia syndromes

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dc.contributor.authorGilley, David Williamen
dc.contributor.committeechairHarrison, David W.en
dc.contributor.committeememberOllendick, Thomas H.en
dc.contributor.committeememberFranchina, Joseph J.en
dc.contributor.committeememberCrawford, Helen J.en
dc.contributor.committeememberWilson, Robert S.en
dc.contributor.departmentPsychologyen
dc.date.accessioned2014-03-14T21:20:49Zen
dc.date.adate2005-10-12en
dc.date.available2014-03-14T21:20:49Zen
dc.date.issued1990-06-15en
dc.date.rdate2005-10-12en
dc.date.sdate2005-10-12en
dc.description.abstractThe concept of subcortical dementia predicts higher rates of depressive symptomatology in dementia syndromes with predominant subcortical pathology. This hypothesis was evaluated by comparing the frequency and severity of depressive symptomatology in three diagnostic conditions: Alzheimer's disease (AD) (n=30) I subcortical vascular disease (SVD) (n=30), and Parkinson's disease (PD) (n=30). While AD and PD are prototypical exemplars of cortical and subcortical dementia syndromes respectively, SVD provides a test of the generality of the hypothesis as a subcortical neurodegenerative condition whose pathology is not confined to a single subcortical nucleus. A secondary aim of the study was to compare assessment methods for the ascertainment of depressive symptomatology. Assessment methods included the Hamilton Rating Scale for depression derived from interview with the patient's primary caregiver (HRSCG) and from interview with the patient (HRSEX), and the self-report Geriatric Depression Scale. The severity of current depressive symptomatology across the three neurodegenerative disorders followed a consistent pattern across each method of assessment. Specifically, scores on self-report (GDS) , examiner ratings (HRSEX), and caregiver ratings (HRSCG) of depression were most severe in patients with Parkinson's disease (PD), intermediate in subcortical vascular disease (SVD), and least severe in Alzheimer's the ascertainment of depressive symptomatology. Assessment methods included the Hamilton Rating Scale for depression derived from interview with the patient's primary caregiver (HRSCG) and from interview with the patient (HRSEX), and the self-report Geriatric Depression Scale. The severity of current depressive symptomatology across the three neurodegenerative disorders followed a consistent pattern across each method of assessment. Specifically, scores on self-report (GDS), examiner ratings (HRSEX), and caregiver ratings (HRSCG) of depression were most severe in patients with Parkinson's disease (PD) , intermediate in subcortical vascular disease (SVD), and least severe in Alzheimer'sen
dc.description.degreePh. D.en
dc.format.extentxvi, 201 leavesen
dc.format.mediumBTDen
dc.format.mimetypeapplication/pdfen
dc.identifier.otheretd-10122005-134413en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-10122005-134413/en
dc.identifier.urihttp://hdl.handle.net/10919/39755en
dc.language.isoenen
dc.publisherVirginia Techen
dc.relation.haspartLD5655.V856_1990.G566.pdfen
dc.relation.isformatofOCLC# 23460168en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.lccLD5655.V856 1990.G566en
dc.subject.lcshDepression, Mental -- Diagnosisen
dc.titleDepression on cortical and subcortical dementia syndromesen
dc.typeDissertationen
dc.type.dcmitypeTexten
thesis.degree.disciplinePsychologyen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.leveldoctoralen
thesis.degree.namePh. D.en

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