Current Thoughts on Maternal Nutrition and Fetal Programming of the Metabolic Syndrome

Brenseke, Bonnie; Prater, Mary R.; Bahamonde, Javiera; Gutierrez, J. Claudio

Current Thoughts on Maternal Nutrition and Fetal Programming of the Metabolic Syndrome

dc.contributor.author	Brenseke, Bonnie	en
dc.contributor.author	Prater, Mary R.	en
dc.contributor.author	Bahamonde, Javiera	en
dc.contributor.author	Gutierrez, J. Claudio	en
dc.date.accessioned	2017-09-18T09:47:14Z	en
dc.date.available	2017-09-18T09:47:14Z	en
dc.date.issued	2013-02-14	en
dc.date.updated	2017-09-18T09:47:14Z	en
dc.description.abstract	Chronic diseases such as type 2 diabetes and cardiovascular disease are the leading cause of death and disability worldwide. Although the metabolic syndrome has been defined in various ways, the ultimate importance of recognizing this combination of disorders is that it helps identify individuals at high risk for both type 2 diabetes and cardiovascular disease. Evidence from observational and experimental studies links adverse exposures in early life, particularly relating to nutrition, to chronic disease susceptibility in adulthood. Such studies provide the foundation and framework for the relatively new field of developmental origins of health and disease (DOHaD). Although great strides have been made in identifying the putative concepts and mechanisms relating specific exposures in early life to the risk of developing chronic diseases in adulthood, a complete picture remains obscure. To date, the main focus of the field has been on perinatal undernutrition and specific nutrient deficiencies; however, the current global health crisis of overweight and obesity demands that perinatal overnutrition and specific nutrient excesses be examined. This paper assembles current thoughts on the concepts and mechanisms behind the DOHaD as they relate to maternal nutrition, and highlights specific contributions made by macro- and micronutrients.	en
dc.description.version	Published version	en
dc.format.mimetype	application/pdf	en
dc.identifier.citation	Bonnie Brenseke, M. Renee Prater, Javiera Bahamonde, and J. Claudio Gutierrez, “Current Thoughts on Maternal Nutrition and Fetal Programming of the Metabolic Syndrome,” Journal of Pregnancy, vol. 2013, Article ID 368461, 13 pages, 2013. doi:10.1155/2013/368461	en
dc.identifier.doi	https://doi.org/10.1155/2013/368461	en
dc.identifier.uri	http://hdl.handle.net/10919/78989	en
dc.language.iso	en	en
dc.publisher	Hindawi	en
dc.rights	Creative Commons Attribution 4.0 International	en
dc.rights.holder	Copyright © 2013 Bonnie Brenseke et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.	en
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	en
dc.title	Current Thoughts on Maternal Nutrition and Fetal Programming of the Metabolic Syndrome	en
dc.title.serial	Journal of Pregnancy	en
dc.type	Article - Refereed	en
dc.type.dcmitype	Text	en