Mapping established psychopathology scales onto the Hierarchical Taxonomy of Psychopathology (HiTOP)

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dc.contributor.authorWendt, Leon P.en
dc.contributor.authorJankowsky, Kristinen
dc.contributor.authorSchroeders, Ulrichen
dc.contributor.authorNolte, Tobiasen
dc.contributor.authorFonagy, Peteren
dc.contributor.authorMontague, P. Readen
dc.contributor.authorZimmermann, Johannesen
dc.contributor.authorOlaru, Gabrielen
dc.date.accessioned2023-05-09T12:43:03Zen
dc.date.available2023-05-09T12:43:03Zen
dc.date.issued2023-05en
dc.description.abstractThe Hierarchical Taxonomy of Psychopathology (HiTOP) organizes phenotypes of mental disorder based on empirical covariation, offering a comprehensive organizational framework from narrow symptoms to broader patterns of psychopathology. We argue that established self-report measures of psychopathology from the pre-HiTOP era should be systematically integrated into HiTOP to foster cumulative research and further the understanding of psychopathology structure. Hence, in this study, we mapped 92 established psychopathology (sub)scales onto the current HiTOP working model using data from an extensive battery of self-report assessments that was completed by community participants and outpatients (N = 909). Content validity ratings of the item pool were used to select indicators for a bifactor-(S-1) model of the p factor and five HiTOP spectra (i.e., internalizing, thought disorder, detachment, disinhibited externalizing, and antagonistic externalizing). The content-based HiTOP scales were validated against personality disorder diagnoses as assessed by standardized interviews. We then located established scales within the taxonomy by estimating the extent to which scales reflected higher-level HiTOP dimensions. The analyses shed light on the location of established psychopathology scales in HiTOP, identifying pure markers and blends of HiTOP spectra, as well as pure markers of the p factor (i.e., scales assessing mentalizing impairment and suspiciousness/epistemic mistrust).en
dc.description.notesThis work was supported by a National Institute for Health Research (NIHR) Senior Investigator Award (NF-SI0514-10157) awarded to Peter Fonagy. The work was also supported by NIH-NIDS Grant 5R01NS092701-03 and a Wellcome Trust Principal Research Fellowship awarded to P. Read Montague.en
dc.description.sponsorshipNational Institute for Health Research (NIHR) Senior Investigator Award [NF-SI0514-10157]; NIH-NIDS [5R01NS092701-03]; Wellcome Trusten
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1002/pmh.1566en
dc.identifier.eissn1932-863Xen
dc.identifier.pmid36162810en
dc.identifier.urihttp://hdl.handle.net/10919/114982en
dc.language.isoenen
dc.publisherWileyen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectValidityen
dc.subjectutilityen
dc.subjectreliabilityen
dc.subjectvalidationen
dc.subjectmodelen
dc.subjectclassificationen
dc.subjectdissociationen
dc.subjectnetworken
dc.titleMapping established psychopathology scales onto the Hierarchical Taxonomy of Psychopathology (HiTOP)en
dc.title.serialPersonality and Mental Healthen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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