Impact of Obesity Subtypes on Short-Term Weight Loss Following Vertical Sleeve Gastrectomy

Background: Temporal prevalence studies of worldwide obesity have confirmed that this epidemic continues to worsen and investigators have suggested that the scope of this problem may indeed be underestimated. The pathogenesis of the condition is multifactorial and complex, and it has been suggested that early life exposure to environmental chemicals (termed obesogens) may be a major cause of this epidemic. Aims: Vertical sleeve gastrectomy has become the most common surgical intervention for medically-complicated obesity. This study was designed to examine the distribution of clinical subtypes of obesity (e.g. psychosocial factors, genetic risk, or obesogens) and to identify the best candidates for vertical sleeve gastrectomy based on clinical subtype. Study Design: This is a retrospective cohort study in a large, urban teaching hospital. Place and Duration of Study: Center for Advanced Laparoscopic & Bariatric Surgery, MedStar Washington Hospital Center Washington, DC between October 2018 and June 2019. Methodology: Consecutive new individuals (n=225) with medically-complicated obesity were evaluated preoperatively in an outpatient bariatric gastroenterology clinic. Subjects (n=17) were excluded. Eighty-four individuals underwent sleeve gastrectomy with a minimum of 6 months of postoperative follow up.