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New approaches to investigating social gestures in autism spectrum disorder

dc.contributor.authorKishida, Kenneth T.en
dc.contributor.authorLi, Jianen
dc.contributor.authorSchwind, Justinen
dc.contributor.authorMontague, P. Readen
dc.date.accessioned2012-09-05T15:06:53Zen
dc.date.available2012-09-05T15:06:53Zen
dc.date.issued2012-05-24en
dc.date.updated2012-09-05T15:06:54Zen
dc.description.abstractThe combination of economic games and human neuroimaging presents the possibility of using economic probes to identify biomarkers for quantitative features of healthy and diseased cognition. These probes span a range of important cognitive functions, but one new use is in the domain of reciprocating social exchange with other humans - a capacity perturbed in a number of psychopathologies. We summarize the use of a reciprocating exchange game to elicit neural and behavioral signatures for subjects diagnosed with autism spectrum disorder (ASD). Furthermore, we outline early efforts to capture features of social exchange in computational models and use these to identify quantitative behavioral differences between subjects with ASD and matched controls. Lastly, we summarize a number of subsequent studies inspired by the modeling results, which suggest new neural and behavioral signatures that could be used to characterize subtle deficits in information processing during interactions with other humans.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationJournal of Neurodevelopmental Disorders. 2012 May 24;4(1):14en
dc.identifier.doihttps://doi.org/10.1186/1866-1955-4-14en
dc.identifier.issue14en
dc.identifier.urihttp://hdl.handle.net/10919/18995en
dc.identifier.volume4en
dc.language.isoenen
dc.publisherBMCen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.holderKenneth T Kishida et al.; licensee BioMed Central Ltd.en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectautism spectrum disorderen
dc.subjectsocial exchangeen
dc.subjectreciprocationen
dc.subjectgame theoryen
dc.subjectcomputational modelsen
dc.subjectfunctional magnetic resonance imagingen
dc.subjectbiomarkeren
dc.titleNew approaches to investigating social gestures in autism spectrum disorderen
dc.title.serialJournal of Neurodevelopmental Disordersen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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