Advancements on the Interface of Computer Experiments and Survival Analysis
| dc.contributor.author | Wang, Yueyao | en |
| dc.contributor.committeechair | Hong, Yili | en |
| dc.contributor.committeechair | Deng, Xinwei | en |
| dc.contributor.committeemember | Kim, Inyoung | en |
| dc.contributor.committeemember | Freeman, Laura J. | en |
| dc.contributor.department | Statistics | en |
| dc.date.accessioned | 2023-06-30T08:02:46Z | en |
| dc.date.available | 2023-06-30T08:02:46Z | en |
| dc.date.issued | 2022-07-20 | en |
| dc.description.abstract | Design and analysis of computer experiments is an area focusing on efficient data collection (e.g., space-filling designs), surrogate modeling (e.g., Gaussian process models), and uncertainty quantification. Survival analysis focuses on modeling the period of time until a certain event happens. Data collection, prediction, and uncertainty quantification are also fundamental in survival models. In this dissertation, the proposed methods are motivated by a wide range of real world applications, including high-performance computing (HPC) variability data, jet engine reliability data, Titan GPU lifetime data, and pine tree survival data. This dissertation is to explore interfaces on computer experiments and survival analysis with the above applications. Chapter 1 provides a general introduction to computer experiments and survival analysis. Chapter 2 focuses on the HPC variability management application. We investigate the applicability of space-filling designs and statistical surrogates in the HPC variability management setting, in terms of design efficiency, prediction accuracy, and scalability. A comprehensive comparison of the design strategies and predictive methods is conducted to study the combinations' performance in prediction accuracy. Chapter 3 focuses on the reliability prediction application. With the availability of multi-channel sensor data, a single degradation index is needed to be compatible with most existing models. We propose a flexible framework with multi-sensory data to model the nonlinear relationship between sensors and the degradation process. We also involve the automatic variable selection to exclude sensors that have no effect on the underlying degradation process. Chapter 4 investigates inference approaches for spatial survival analysis under the Bayesian framework. The Markov chain Monte Carlo (MCMC) approaches and variational inferences performance are studied for two survival models, the cumulative exposure model and the proportional hazard (PH) model. The Titan GPU data and pine tree survival data are used to illustrate the capability of variational inference on spatial survival models. Chapter 5 provides some general conclusions. | en |
| dc.description.abstractgeneral | This dissertation focus on three projects related to computer experiments and survival analysis. Design and analysis of the computer experiment is an area focusing on efficient data collection, building predictive models, and uncertainty quantification. Survival analysis focuses on modeling the period of time until a certain event happens. Data collection, prediction, and uncertainty quantification are also fundamental in survival models. Thus, this dissertation aims to explore interfaces between computer experiments and survival analysis with real world applications. High performance computing systems aggregate a large number of computers to achieve high computing speed. The first project investigates the applicability of space-filling designs and statistical predictive models in the HPC variability management setting, in terms of design efficiency, prediction accuracy, and scalability. A comprehensive comparison of the design strategies and predictive methods is conducted to study the combinations' performance in prediction accuracy. The second project focuses on building a degradation index that describes the product's underlying degradation process. With the availability of multi-channel sensor data, a single degradation index is needed to be compatible with most existing models. We propose a flexible framework with multi-sensory data to model the nonlinear relationship between sensors and the degradation process. We also involve the automatic variable selection to exclude sensors that have no effect on the underlying degradation process. The spatial survival data are often observed when the survival data are collected over a spatial region. The third project studies inference approaches for spatial survival analysis under the Bayesian framework. The commonly used inference method, Markov chain Monte Carlo (MCMC) approach and the approximate inference approach, variational inference's performance are studied for two survival models. The Titan GPU data and pine tree survival data are used to illustrate the capability of variational inference on spatial survival models. | en |
| dc.description.degree | Doctor of Philosophy | en |
| dc.format.medium | ETD | en |
| dc.identifier.other | vt_gsexam:35285 | en |
| dc.identifier.uri | http://hdl.handle.net/10919/115601 | en |
| dc.language.iso | en | en |
| dc.publisher | Virginia Tech | en |
| dc.rights | In Copyright | en |
| dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | en |
| dc.subject | Computer Experiments-Degradation Index-Survival Analysis-System Health Monitoring-Variational Inference | en |
| dc.title | Advancements on the Interface of Computer Experiments and Survival Analysis | en |
| dc.type | Dissertation | en |
| thesis.degree.discipline | Statistics | en |
| thesis.degree.grantor | Virginia Polytechnic Institute and State University | en |
| thesis.degree.level | doctoral | en |
| thesis.degree.name | Doctor of Philosophy | en |
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