Ethambutol-induced bullous skin lesions in mycobacterium kansasii lung infection

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dc.contributor.authorKollipara, Venkateswaraen
dc.contributor.authorHorowitz, Mitchellen
dc.contributor.authorLantz, Jefferyen
dc.contributor.authorNagy-Agren, Stephanie E.en
dc.date.accessioned2022-09-30T16:53:53Zen
dc.date.available2022-09-30T16:53:53Zen
dc.date.issued2022-03-12en
dc.date.updated2022-09-30T16:36:03Zen
dc.description.abstractMycobacterium kansasii is the second most common cause of nontuberculous mycobacterial (NTM) lung disease after Mycobacterium avium complex infection in the United States. [1] The first-line therapy for M. kansasii is a three-drug regimen including rifampin, isoniazid, and ethambutol. We present a case of a patient with pulmonary M. kansasii who developed bullous skin lesions while receiving this regimen and again after rechallenge with ethambutol. In patients with intolerance to one of the first-line antibiotics, a multidisciplinary team approach to starting second-line agents is needed. Ethambutol should be included in the differential diagnosis of drug-induced bullous skin lesions in treated patients with NTM, who develop new onset rash with blisters or ulceration.en
dc.description.versionPublished versionen
dc.format.extentPages 120-122en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.4103/ijmy.ijmy_204_21en
dc.identifier.eissn2212-554Xen
dc.identifier.issn2212-5531en
dc.identifier.issue1en
dc.identifier.orcidNagy-Agren, Stephanie [0000-0003-2481-196X]en
dc.identifier.otherIntJMycobacteriol_2022_11_1_120_339504 (PII)en
dc.identifier.pmid35295035en
dc.identifier.urihttp://hdl.handle.net/10919/112040en
dc.identifier.volume11en
dc.language.isoenen
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pubmed/35295035en
dc.rightsCreative Commons Attribution-NonCommercial-ShareAlike 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/en
dc.subjectDirect immunofluorescenten
dc.subjectMycobacterium kansasiien
dc.subjectdrug-induced skin reactionsen
dc.subjectethambutolen
dc.subjectpemphigus vulgarisen
dc.subjectsuprabasilar bullous skin lesionen
dc.subjectOrphan Drugen
dc.subjectRare Diseasesen
dc.subjectTuberculosisen
dc.subjectLungen
dc.subject2 Aetiologyen
dc.subject2.1 Biological and endogenous factorsen
dc.subjectInfectionen
dc.subject.meshLungen
dc.subject.meshHumansen
dc.subject.meshMycobacterium kansasiien
dc.subject.meshMycobacterium avium-intracellulare Infectionen
dc.subject.meshEthambutolen
dc.subject.meshIsoniaziden
dc.subject.meshMycobacterium Infections, Nontuberculousen
dc.titleEthambutol-induced bullous skin lesions in mycobacterium kansasii lung infectionen
dc.title.serialInternational Journal of Mycobacteriologyen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherJournal Articleen
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicineen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicine/Internal Medicineen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicine/VTC School of Medicine - Instr Pgmsen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicine/Internal Medicine/General IMen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicine/VTC School of Medicine - Instr Pgms/VTC School of Medicine-Instr Pgmsen

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