Autonomic Nervous System Correlates of Emotion Regulation in Autistic Adults

Emotion regulation difficulty is commonly experienced by autistic adults and has been explored as a transdiagnostic mechanism contributing to anxiety and depression in autistic adults. Previous research has found that emotion regulation strategies and autonomic nervous system (ANS) responses involved in emotion regulation differ between autistic and non-autistic individuals. These findings highlight the role of the ANS as a measure of emotion regulation; however, this has not been studied in an autistic adult sample. The current study examined ANS activity, as measured by respiratory sinus arrhythmia (RSA), root mean square successive differences (rMSSD), and skin conductance level (SCL), and subjective ratings of valence and arousal at rest and while viewing emotional film clips and engaging in emotion regulation in autistic adults. The study consisted of 31 autistic and 31 non-autistic adults, matched on age, intellectual ability, sex, and race/ethnicity. Participants also self-reported their daily emotion regulation use via the Emotion Regulation Questionnaire. Results demonstrated group differences in baseline RSA and rMSSD, self-reported valence of viewing neutral and negative stimuli, and cognitive reappraisal used in daily life. There was also increased SCL and self-reported arousal and decreased self-reported valence to negative stimuli across the whole sample. Exploratory results also showed that SCL and self-reported arousal to negative stimuli were correlated for autistic participants, and that emotion regulation changed physiological and subjective experiences of negative emotion across the whole sample. Supplementary analyses explored the covarying role of co-occurring depression and anxiety and antidepressant use, and showed that these covariates may explain variance in some physiological and self-reported responses whereas in other models, they may suppress these changes. This study extends previous research on emotion regulation in daily life of autistic adults and is the first investigation that demonstrates how an objective measure, such as correlates of ANS, provides additional insight in emotion regulation in autistic adults beyond subjective ratings. This study is important insofar as it shows how emotion regulation strategies manifest in autistic adults and its implications for informing the use of emotion regulation treatment intervention.