THC and CBD: Villain versus Hero? Insights into Adolescent Exposure

dc.contributor.authorPintori, Nicholasen
dc.contributor.authorCaria, Francescaen
dc.contributor.authorDe Luca, Maria Antoniettaen
dc.contributor.authorMiliano, Cristinaen
dc.date.accessioned2023-03-10T14:09:02Zen
dc.date.available2023-03-10T14:09:02Zen
dc.date.issued2023-03-09en
dc.date.updated2023-03-10T14:01:50Zen
dc.description.abstractCannabis is the most used drug of abuse worldwide. It is well established that the most abundant phytocannabinoids in this plant are Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). These two compounds have remarkably similar chemical structures yet vastly different effects in the brain. By binding to the same receptors, THC is psychoactive, while CBD has anxiolytic and antipsychotic properties. Lately, a variety of hemp-based products, including CBD and THC, have become widely available in the food and health industry, and medical and recreational use of cannabis has been legalized in many states/countries. As a result, people, including youths, are consuming CBD because it is considered “safe”. An extensive literature exists evaluating the harmful effects of THC in both adults and adolescents, but little is known about the long-term effects of CBD exposure, especially in adolescence. The aim of this review is to collect preclinical and clinical evidence about the effects of cannabidiol.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationPintori, N.; Caria, F.; De Luca, M.A.; Miliano, C. THC and CBD: Villain versus Hero? Insights into Adolescent Exposure. Int. J. Mol. Sci. 2023, 24, 5251.en
dc.identifier.doihttps://doi.org/10.3390/ijms24065251en
dc.identifier.urihttp://hdl.handle.net/10919/114075en
dc.language.isoenen
dc.publisherMDPIen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectTHCen
dc.subjectCBDen
dc.subjectadolescenceen
dc.titleTHC and CBD: Villain versus Hero? Insights into Adolescent Exposureen
dc.title.serialInternational Journal of Molecular Scienceen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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