Analysis of SNHG14: A Long Non-Coding RNA Hosting SNORD116, Whose Loss Contributes to Prader-Willi Syndrome Etiology

Simple item page
dc.contributor.authorAriyanfar, Shadien
dc.contributor.authorGood, Deborah J.en
dc.date.accessioned2023-01-06T15:50:48Zen
dc.date.available2023-01-06T15:50:48Zen
dc.date.issued2022-12-29en
dc.date.updated2023-01-06T13:52:25Zen
dc.description.abstractThe Small Nucleolar Host Gene 14 (<i>SNHG14</i>) is a host gene for small non-coding RNAs, including the <i>SNORD116</i> small nucleolar C/D box RNA encoding locus. Large deletions of the <i>SNHG14</i> locus, as well as microdeletions of the <i>SNORD116</i> locus, lead to the neurodevelopmental genetic disorder Prader&ndash;Willi syndrome. This review will focus on the <i>SNHG14</i> gene, its expression patterns, its role in human cancer, and the possibility that single nucleotide variants within the locus contribute to human phenotypes in the general population. This review will also include new in silico data analyses of the <i>SNHG14</i> locus and new in situ RNA expression patterns of the Snhg14 RNA in mouse midbrain and hindbrain regions.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationAriyanfar, S.; Good, D.J. Analysis of SNHG14: A Long Non-Coding RNA Hosting SNORD116, Whose Loss Contributes to Prader-Willi Syndrome Etiology. Genes 2022, 14, 97.en
dc.identifier.doihttps://doi.org/10.3390/genes14010097en
dc.identifier.urihttp://hdl.handle.net/10919/113077en
dc.language.isoenen
dc.publisherMDPIen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectsmall nucleolar RNAen
dc.subjectUBE3A-ATSen
dc.subjectHBIII-85en
dc.subjectPET1en
dc.subjectPWCR1en
dc.subjectcanceren
dc.subjectimmunityen
dc.subjectIL-8en
dc.titleAnalysis of SNHG14: A Long Non-Coding RNA Hosting SNORD116, Whose Loss Contributes to Prader-Willi Syndrome Etiologyen
dc.title.serialGenesen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
genes-14-00097.pdf
Size:
3.48 MB
Format:
Adobe Portable Document Format
Description:
Published version
Download
License bundle
Now showing 1 - 1 of 1
Name:
license.txt
Size:
0 B
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Journal Articles, Multidisciplinary Digital Publishing Institute (MDPI)
Scholarly Works, Human Nutrition, Foods, and Exercise