Peptide-based hydrogen sulphide-releasing gels

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Date

2015-07-20

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Publisher

The Royal Society of Chemistry

Abstract

An aromatic peptide amphiphile was designed for delivery of the signaling gas H2S. The peptide self-assembled in water into nanofibers that gelled upon charge screening. The non-toxic gel slowly released H2S over 15 hours, and the presence of H2S in endothelial cells was verified using a fluorescent H2S probe.

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Citation

Carter, J. M., Qian, Y., Foster, J. C., & Matson, J. B. (2015). Peptide-based hydrogen sulphide-releasing gels. Chemical Communications, 51(66), 13131-13134. doi:10.1039/C5CC04883D