The synthesis of some substituted 7-(1-Naphthyl)- Benz(a)Anthracenes

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dc.contributor.authorLewis, Claude Ireniusen
dc.contributor.committeechairVingiello, Frank A.en
dc.contributor.departmentChemistryen
dc.date.accessioned2014-03-14T21:23:13Zen
dc.date.adate2012-11-29en
dc.date.available2014-03-14T21:23:13Zen
dc.date.issued1962-06-15en
dc.date.rdate2012-11-29en
dc.date.sdate2012-11-29en
dc.description.abstractMany benz(a)anthracene derivatives are able to produce cancer in the experimental animal. There is a correlation between the calculated total electronic charge of the K-region and this carcinogenic activity. There is also ample proof that benz(a)anthracene derivatives are honed to the skin through quinoid type bonds in the K"region. However, the prediction of physiological activity of benz(a)anthracenes is still unreliable because of the limitations of the theoretical model described by existing theories. The purpose of this work was to synthesize some substituted benz(a)anthracenes with a shielded K-region and with a different L-region electron density than in 7-phenyl-bena(a)anthracene in the hope of increasing our knowledge regarding molecular structure-physiological relationship.en
dc.description.degreePh. D.en
dc.format.extent178 leavesen
dc.format.mediumBTDen
dc.format.mimetypeapplication/pdfen
dc.identifier.otheretd-11292012-040216en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-11292012-040216/en
dc.identifier.urihttp://hdl.handle.net/10919/40361en
dc.language.isoenen
dc.publisherVirginia Techen
dc.relation.haspartLD5655.V856_1962.L488.pdfen
dc.relation.isformatofOCLC# 20269249en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.lccLD5655.V856 1962.L488en
dc.subject.lcshBenzanthracenesen
dc.subject.lcshPolycyclic compounds -- Synthesisen
dc.titleThe synthesis of some substituted 7-(1-Naphthyl)- Benz(a)Anthracenesen
dc.typeDissertationen
dc.type.dcmitypeTexten
thesis.degree.disciplineChemistryen
thesis.degree.grantorVirginia Polytechnic Instituteen
thesis.degree.leveldoctoralen
thesis.degree.namePh. D.en

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