Infectious SARS-CoV-2 Is Emitted in Aerosol Particles
dc.contributor.author | Hawks, Seth A. | en |
dc.contributor.author | Prussin, Aaron J. II | en |
dc.contributor.author | Kuchinsky, Sarah C. | en |
dc.contributor.author | Pan, Jin | en |
dc.contributor.author | Marr, Linsey C. | en |
dc.contributor.author | Duggal, Nisha K. | en |
dc.date.accessioned | 2021-10-22T13:41:35Z | en |
dc.date.available | 2021-10-22T13:41:35Z | en |
dc.date.issued | 2021-10-19 | en |
dc.description.abstract | Respiratory viruses such as SARS-CoV-2 are transmitted in respiratory droplets and aerosol particles, which are released during talking, breathing, coughing, and sneezing. Noncontact transmission of SARS-CoV-2 has been demonstrated, suggesting transmission via virus carried through the air. Here, we demonstrate that golden Syrian hamsters produce infectious SARS-CoV-2 in aerosol particles prior to and concurrent with the onset of mild clinical signs of disease. The average emission rate in this study was 25 infectious virions/hour on days 1 and 2 postinoculation, with average viral RNA levels 200-fold higher than infectious virus in aerosol particles. The majority of virus was contained within particles <5 μm in size. Thus, we provide direct evidence that, in hamsters, SARS-CoV-2 is an airborne virus. | en |
dc.description.version | Published version | en |
dc.format.mimetype | application/pdf | en |
dc.identifier.doi | https://doi.org/10.1128/mBio.02527-21 | en |
dc.identifier.issue | 5 | en |
dc.identifier.uri | http://hdl.handle.net/10919/105633 | en |
dc.identifier.volume | 12 | en |
dc.language.iso | en | en |
dc.publisher | American Society for Microbiology | en |
dc.rights | Creative Commons Attribution 4.0 International | en |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en |
dc.subject | animal models | en |
dc.subject | coronavirus | en |
dc.subject | transmission | en |
dc.title | Infectious SARS-CoV-2 Is Emitted in Aerosol Particles | en |
dc.title.serial | mBio | en |
dc.type | Article - Refereed | en |
dc.type.dcmitype | Text | en |