Factors associated with the risk of positive blood culture in neonatal foals presented to a referral center (2000-2014)

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dc.contributor.authorFurr, Martinen
dc.contributor.authorMcKenzie, Harolden
dc.contributor.departmentLarge Animal Clinical Sciencesen
dc.date.accessioned2021-09-02T14:46:45Zen
dc.date.available2021-09-02T14:46:45Zen
dc.date.issued2020-10-12en
dc.date.updated2021-09-02T14:46:42Zen
dc.description.abstractBackground: Bloodstream infections (BSI) are common in sick foals and increase foal morbidity and mortality when they occur. Recognition of risk factors for BSI could be an important means to limit their occurrence, but studies on this topic are limited. Objectives: Historical as well as maternal and foal physical examination findings will predict risk of BSI in neonatal foals. Animals: Foals <14 days of age admitted to a referral equine hospital for care. Methods: Retrospective case-control study with univariate and multivariable logistic regression analysis. Results: Four hundred twenty-nine (143 cases and 286 controls) foals <14 days of age were studied. Risk of a foal having a BSI was increased in foals with umbilical disease (adjusted odds ratio [OR], 11.01; P =.02), hypoglycemia (adjusted OR, 13.51; P =.03), and the combined presence of umbilical disease and low hematocrit (adjusted OR, >999.99; P =.04). Factors not found to be risk factors for development of BSI included prematurity, hypothermia, abdominal disease, diarrhea, failure of passive transfer, and maternal uterine infection. Conclusions and Clinical Importance: Several historical and physical examination findings increase the risk of foals being blood culture positive at presentation to the hospital. This knowledge may aid early identification of blood culture status, thus aiding in treatment decisions.en
dc.description.versionPublished versionen
dc.format.extentPages 2738-2750en
dc.format.extent13 page(s)en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1111/jvim.15923en
dc.identifier.eissn1939-1676en
dc.identifier.issn0891-6640en
dc.identifier.issue6en
dc.identifier.orcidMcKenzie, Harold [0000-0001-8230-2237]en
dc.identifier.pmid33044020en
dc.identifier.urihttp://hdl.handle.net/10919/104900en
dc.identifier.volume34en
dc.language.isoenen
dc.publisherWileyen
dc.relation.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000579152800001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=930d57c9ac61a043676db62af60056c1en
dc.rightsCreative Commons Attribution-NonCommercial 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectLife Sciences & Biomedicineen
dc.subjectVeterinary Sciencesen
dc.subjectbacteremiaen
dc.subjectfoalen
dc.subjectneonateen
dc.subjectsepticemiaen
dc.subjectCRITICALLY-ILL PATIENTSen
dc.subjectLACTATE CONCENTRATIONen
dc.subjectSTREAM INFECTIONSen
dc.subjectSCORING SYSTEMen
dc.subjectSEPSIS SCOREen
dc.subjectSURVIVALen
dc.subjectDIAGNOSISen
dc.subjectDEATHen
dc.subjectSUSCEPTIBILITYen
dc.subjectHYPOGLYCEMIAen
dc.subject0707 Veterinary Sciencesen
dc.subject.meshAnimalsen
dc.subject.meshAnimals, Newbornen
dc.subject.meshHorsesen
dc.subject.meshHorse Diseasesen
dc.subject.meshCase-Control Studiesen
dc.subject.meshRetrospective Studiesen
dc.subject.meshReferral and Consultationen
dc.subject.meshBlood Cultureen
dc.titleFactors associated with the risk of positive blood culture in neonatal foals presented to a referral center (2000-2014)en
dc.title.serialJournal of Veterinary Internal Medicineen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherArticleen
dc.type.otherJournalen
dcterms.dateAccepted2020-09-22en
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/Veterinary Medicineen
pubs.organisational-group/Virginia Tech/Veterinary Medicine/Large Animal Clinical Sciencesen
pubs.organisational-group/Virginia Tech/All T&R Facultyen
pubs.organisational-group/Virginia Tech/Veterinary Medicine/CVM T&R Facultyen

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