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Nanotechnology for immuno-oncology

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dc.contributor.authorGrippin, Adam J.en
dc.contributor.authorLee, DaeYongen
dc.contributor.authorParkes, Eileen E.en
dc.contributor.authorJiang, Wenen
dc.contributor.authorKim, Betty Y. S.en
dc.date.accessioned2025-10-09T12:29:28Zen
dc.date.available2025-10-09T12:29:28Zen
dc.date.issued2025-08-01en
dc.description.abstractAlthough the first generation of cancer immunotherapeutics produced unprecedented improvements in clinical outcomes for individuals with cancer, novel strategies to increase treatment specificity, delivery efficiency and pharmacokinetics are still needed. In this Review, we describe the potential advantages and current limitations of nanomaterials for cancer immunotherapy and highlight rational uses of nanosystems to generate potent and durable antitumor immune responses. We close with a review of the current state of clinical development of nanomedicine for cancer immunotherapy.en
dc.description.versionAccepted versionen
dc.format.extentPages 1311-1325en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1038/s43018-025-01025-xen
dc.identifier.eissn2662-1347en
dc.identifier.issn2662-1347en
dc.identifier.issue8en
dc.identifier.orcidLee, DaeYong [0000-0001-8485-3577]en
dc.identifier.other10.1038/s43018-025-01025-x (PII)en
dc.identifier.pmid40775548en
dc.identifier.urihttps://hdl.handle.net/10919/138105en
dc.identifier.volume6en
dc.language.isoenen
dc.publisherNature Portfolioen
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pubmed/40775548en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectImmunotherapyen
dc.subjectNanotechnologyen
dc.subject.meshAnimalsen
dc.subject.meshHumansen
dc.subject.meshNeoplasmsen
dc.subject.meshImmunotherapyen
dc.subject.meshMedical Oncologyen
dc.subject.meshNanotechnologyen
dc.subject.meshNanostructuresen
dc.subject.meshNanomedicineen
dc.subject.meshNanoparticlesen
dc.titleNanotechnology for immuno-oncologyen
dc.title.serialNature Canceren
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dcterms.dateAccepted2025-06-11en
pubs.organisational-groupVirginia Techen
pubs.organisational-groupVirginia Tech/All T&R Facultyen
pubs.organisational-groupVirginia Tech/University Research Institutesen
pubs.organisational-groupVirginia Tech/University Research Institutes/Fralin Biomedical Research Institute at VTCen

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