Biosynthesis and possible functions of inositol pyrophosphates in plants

Simple item page
dc.contributor.authorWilliams, Sarah P.en
dc.contributor.authorGillaspy, Glenda E.en
dc.contributor.authorPerera, Imara Y.en
dc.contributor.departmentBiochemistryen
dc.date.accessioned2017-01-04T22:07:16Zen
dc.date.available2017-01-04T22:07:16Zen
dc.date.issued2015-02-12en
dc.description.abstractInositol phosphates (InsPs) are intricately tied to lipid signaling, as at least one portion of the inositol phosphate signaling pool is derived from hydrolysis of the lipid precursor, phosphatidyl inositol (4,5) bisphosphate. The focus of this review is on the inositol pyrophosphates, which are a novel group of InsP signaling molecules containing diphosphate or triphosphate chains (i.e., PPx) attached to the inositol ring. These PPx-InsPs are emerging as critical players in the integration of cellular metabolism and stress signaling in non-plante ukaryotes. Most eukaryotes synthesize the precursor molecule, myo-inositol (1,2,3,4,5,6)-hexakisphosphate (InsP6), which can serve as a signaling molecule or as storage compound of inositol, phosphorus, and minerals( referred to as phytic acid). Even though plants produce huge amounts of precursor InsP6 in seeds, almost no attention has been paid to whether PPx-InsPs exist in plants, and if so, what roles these molecules play. Recent work has delineated that Arabidopsis has two genes capable of PP-InsP5 synthesis, and PPx-InsPs have been detected across the plant kingdom. This review will detail the known roles of PPx-InsPs in yeast and animal systems, and provide a description of recent data on the synthesis and accumulation of these novel molecules in plants, and potential roles in signaling.en
dc.description.versionPublished versionen
dc.format.extent? - ? (12) page(s)en
dc.identifier.doihttps://doi.org/10.3389/fpls.2015.00067en
dc.identifier.issn1664-462Xen
dc.identifier.urihttp://hdl.handle.net/10919/73942en
dc.identifier.volume6en
dc.language.isoenen
dc.publisherFrontiersen
dc.relation.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000349235500002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=930d57c9ac61a043676db62af60056c1en
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectPlant Sciencesen
dc.subjectplant inositol signalingen
dc.subjectinositol hexakisphosphateen
dc.subjectVIPen
dc.subjectinositol pyrophosphateen
dc.subjectenergy metabolismen
dc.subjectXENOPUS-LAEVIS OOCYTESen
dc.subjectCYCLIN-CDK COMPLEXen
dc.subjectDIPHOSPHOINOSITOL PENTAKISPHOSPHATEen
dc.subjectCELL-DEATHen
dc.subjectHEXAKISPHOSPHATE KINASEen
dc.subjectGUARD-CELLSen
dc.subjectSACCHAROMYCES-CEREVISIAEen
dc.subjectPHOSPHATE HOMEOSTASISen
dc.subjectPOLYPHOSPHATE KINASESen
dc.subjectTRANSPORTER ATMRP5en
dc.titleBiosynthesis and possible functions of inositol pyrophosphates in plantsen
dc.title.serialFrontiers in Plant Scienceen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciencesen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/Biochemistryen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/CALS T&R Facultyen
pubs.organisational-group/Virginia Tech/All T&R Facultyen

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Biosynthesis and possible functions of inositol pyrophosphates in plants.pdf
Size:
3.39 MB
Format:
Adobe Portable Document Format
Description:
Publisher's Version
Download
License bundle
Now showing 1 - 1 of 1
Name:
VTUL_Distribution_License_2016_05_09.pdf
Size:
18.09 KB
Format:
Adobe Portable Document Format
Description:
Download

Collections

All Faculty Deposits
Scholarly Works, Biochemistry