Outcome of In-Hospital Cardiac Arrest among Patients with COVID-19: A Systematic Review and Meta-Analysis
| dc.contributor.author | Shrestha, Dhan Bahadur | en |
| dc.contributor.author | Sedhai, Yub Raj | en |
| dc.contributor.author | Dawadi, Sagun | en |
| dc.contributor.author | Dhakal, Bishal | en |
| dc.contributor.author | Shtembari, Jurgen | en |
| dc.contributor.author | Singh, Karan | en |
| dc.contributor.author | Acharya, Roshan | en |
| dc.contributor.author | Basnyat, Soney | en |
| dc.contributor.author | Waheed, Irfan | en |
| dc.contributor.author | Khan, Mohammad Saud | en |
| dc.contributor.author | Kazimuddin, Mohammed | en |
| dc.contributor.author | Patel, Nimesh K. | en |
| dc.contributor.author | Kalahasty, Gautham | en |
| dc.contributor.author | Bhave, Prashant Dattatraya | en |
| dc.contributor.author | Whalen, Patrick | en |
| dc.contributor.author | Shantha, Ghanshyam | en |
| dc.date.accessioned | 2023-04-12T16:28:25Z | en |
| dc.date.available | 2023-04-12T16:28:25Z | en |
| dc.date.issued | 2023-04-10 | en |
| dc.date.updated | 2023-04-12T13:24:32Z | en |
| dc.description.abstract | Background: Outcomes following in-hospital cardiac arrest (IHCA) in patients with COVID-19 have been reported by several small single-institutional studies; however, there are no large studies contrasting COVID-19 IHCA with non-COVID-19 IHCA. The objective of this study was to compare the outcomes following IHCA between COVID-19 and non-COVID-19 patients. Methods: We searched databases using predefined search terms and appropriate Boolean operators. All the relevant articles published till August 2022 were included in the analyses. The systematic review and meta-analysis were conducted as per Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. An odds ratio with a 95% confidence interval (CI) was used to measure effects. Results: Among 855 studies screened, 6 studies with 27,453 IHCA patients (63.84% male) with COVID-19 and 20,766 (59.7% male) without COVID-19 were included in the analysis. IHCA among patients with COVID-19 has lower odds of achieving return of spontaneous circulation (ROSC) (OR: 0.66, 95% CI: 0.62–0.70). Similarly, patients with COVID-19 have higher odds of 30-day mortality following IHCA (OR: 2.26, 95% CI: 2.08–2.45) and have 45% lower odds of cardiac arrest because of a shockable rhythm (OR: 0.55, 95% CI: 0.50–0.60) (9.59% vs. 16.39%). COVID-19 patients less commonly underwent targeted temperature management (TTM) or coronary angiography; however, they were more commonly intubated and on vasopressor therapy as compared to patients who did not have a COVID-19 infection. Conclusions: This meta-analysis showed that IHCA with COVID-19 has a higher mortality and lower rates of ROSC compared with non-COVID-19 IHCA. COVID-19 is an independent risk factor for poor outcomes in IHCA patients. | en |
| dc.description.version | Published version | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.citation | Shrestha, D.B.; Sedhai, Y.R.; Dawadi, S.; Dhakal, B.; Shtembari, J.; Singh, K.; Acharya, R.; Basnyat, S.; Waheed, I.; Khan, M.S.; Kazimuddin, M.; Patel, N.K.; Kalahasty, G.; Bhave, P.D.; Whalen, P.; Shantha, G. Outcome of In-Hospital Cardiac Arrest among Patients with COVID-19: A Systematic Review and Meta-Analysis. J. Clin. Med. 2023, 12, 2796. | en |
| dc.identifier.doi | https://doi.org/10.3390/jcm12082796 | en |
| dc.identifier.uri | http://hdl.handle.net/10919/114488 | en |
| dc.language.iso | en | en |
| dc.publisher | MDPI | en |
| dc.rights | Creative Commons Attribution 4.0 International | en |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en |
| dc.subject | COVID-19 | en |
| dc.subject | in-hospital cardiac arrest | en |
| dc.subject | mortality | en |
| dc.title | Outcome of In-Hospital Cardiac Arrest among Patients with COVID-19: A Systematic Review and Meta-Analysis | en |
| dc.title.serial | Journal of Clinical Medicine | en |
| dc.type | Article - Refereed | en |
| dc.type.dcmitype | Text | en |