Selection for serum cholesterol, voluntary physical activity, 56- day body weight and feed intake in albino mice

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dc.contributor.authorDunnington, E. Annen
dc.contributor.committeechairWhite, John M.en
dc.contributor.committeememberVinson, William E.en
dc.contributor.committeememberSiegel, Paul B.en
dc.contributor.committeememberHinkelmann, Klaus H.en
dc.contributor.committeememberThye, Forrest W.en
dc.contributor.departmentGeneticsen
dc.date.accessioned2014-03-14T21:23:14Zen
dc.date.adate2012-11-29en
dc.date.available2014-03-14T21:23:14Zen
dc.date.issued1978-01-15en
dc.date.rdate2012-11-29en
dc.date.sdate2012-11-29en
dc.description.abstractA short-term selection experiment was conducted with ICR albino mice produced by the reciprocal crossing of two lines of unselected animals which had been random-bred for 28 generations. Lines were developed by selecting for maximum and minimum serum cholesterol (SC) (lines CH and CL), voluntary physical activity (lines AH and AL), 56-day body weight (lines WH and WL) and feed intake (lines IH and IL). An unselected, random-bred control line was maintained with each pair of divergent selected lines (CC, AC, NC and IC, respectively). In the lines selected for SC, physical activity and 56-day body weight, selection was based on individual performance. Twenty-five paired matings plus five extra paired matings were used to perpetuate the lines each generation for five generations. The feed intake lines were perpetuated by within-sex, full-sib family selection with 30 paired matings per generation for five generations.en
dc.description.degreePh. D.en
dc.format.extentx, 145 leavesen
dc.format.mediumBTDen
dc.format.mimetypeapplication/pdfen
dc.identifier.otheretd-11292012-040248en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-11292012-040248/en
dc.identifier.urihttp://hdl.handle.net/10919/40368en
dc.language.isoenen
dc.publisherVirginia Techen
dc.relation.haspartLD5655.V856_1978.D85.pdfen
dc.relation.isformatofOCLC# 22431505en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.lccLD5655.V856 1978.D85en
dc.subject.lcshBlood cholesterolen
dc.subject.lcshMiceen
dc.titleSelection for serum cholesterol, voluntary physical activity, 56- day body weight and feed intake in albino miceen
dc.typeDissertationen
dc.type.dcmitypeTexten
thesis.degree.disciplineGeneticsen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.leveldoctoralen
thesis.degree.namePh. D.en

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