Electrochemotherapy (ECT) and irreversible electroporation (IRE) -advanced techniques for treating deep-seated tumors based on electroporation

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dc.contributor.authorMiklavčič, Damijanen
dc.contributor.authorDavalos, Rafael V.en
dc.contributor.departmentSchool of Biomedical Engineering and Sciencesen
dc.date.accessioned2016-01-15T17:02:20Zen
dc.date.available2016-01-15T17:02:20Zen
dc.date.issued2015-08-27en
dc.date.updated2016-01-15T17:02:20Zen
dc.description.abstractWhen a cell is exposed to a sufficiently intense electric field (for a sufficient duration), local defects in the cell membrane appear and become permeable to molecules that otherwise cannot pass through it. This phenomenon is commonly known as electroporation but additional terms electropermeabilization and PEF (i.e. pulsed electric field) treatment are commonly used as well (the latter mainly in food processing area). In reversible electroporation, cell membrane permeabilization to molecules otherwise deprived of transmembrane transport mechanisms is a transient phenomenon as after some time membrane reseals and reestablishes its homeostatic semipermeable properties, allowing ions and other small molecules to passively cross...en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationBioMedical Engineering OnLine. 2015 Aug 27;14(Suppl 3):I1en
dc.identifier.doihttps://doi.org/10.1186/1475-925X-14-S3-I1en
dc.identifier.urihttp://hdl.handle.net/10919/64462en
dc.language.isoenen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.holderMiklavcic and Davalos;en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.titleElectrochemotherapy (ECT) and irreversible electroporation (IRE) -advanced techniques for treating deep-seated tumors based on electroporationen
dc.title.serialBioMedical Engineering OnLineen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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