Semiparametric change points detection using single index spatial random effects model in environmental epidemiology study

dc.contributor.authorMahmoud, Hamdy F. F.en
dc.contributor.authorKim, Inyoungen
dc.date.accessioned2025-02-18T12:55:48Zen
dc.date.available2025-02-18T12:55:48Zen
dc.date.issued2024-12-12en
dc.description.abstractEnvironmental health studies are of great interest in research to evaluate the mortality-temperature relationship by adjusting spatially correlated random effects as well as identifying significant change points in temperature. However, this relationship is often not expressed using parametric models, which makes identifying change points an even more challenging problem. This paper proposes a unified semiparametric approach to simultaneously identify the nonlinear mortality-temperature relationship and detect spatially-dependent change points. A unified method is proposed for the model estimation, spatially dependent change points detection, and testing whether they are significant simultaneously by a permutation-based test. We operate under the assumption that change points remain constant, yet acknowledge the uncertainty regarding their precise number. These change points are influenced by the smoothing of an unknown function, which in turn relies on a smoothing variable and spatial random effects. Consequently, the detection of change points may be influenced by spatial effects. In this paper, several simulation studies are conducted to evaluate the performance of our proposed approach. The advantages of this unified approach are demonstrated using epidemiological data on mortality and temperature.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1371/journal.pone.0315413en
dc.identifier.eissn1932-6203en
dc.identifier.issn1932-6203en
dc.identifier.orcidMahmoud, Hamdy [0000-0001-8378-2965]en
dc.identifier.otherPONE-D-24-07235 (PII)en
dc.identifier.pmid39666670en
dc.identifier.urihttps://hdl.handle.net/10919/124609en
dc.identifier.volume19en
dc.language.isoenen
dc.publisherPublic Library of Scienceen
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pubmed/39666670en
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subject.meshHumansen
dc.subject.meshMortalityen
dc.subject.meshModels, Statisticalen
dc.subject.meshEpidemiologic Studiesen
dc.subject.meshEnvironmental Healthen
dc.subject.meshTemperatureen
dc.subject.meshComputer Simulationen
dc.titleSemiparametric change points detection using single index spatial random effects model in environmental epidemiology studyen
dc.title.serialPLoS ONEen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherJournal Articleen
dcterms.dateAccepted2024-11-25en
pubs.organisational-groupVirginia Techen
pubs.organisational-groupVirginia Tech/Scienceen
pubs.organisational-groupVirginia Tech/Science/Statisticsen

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