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PATRIC: The VBI PathoSystems Resource Integration Center

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dc.contributor.authorSnyder, E. E.en
dc.contributor.authorKampanya, N.en
dc.contributor.authorLu, J.en
dc.contributor.authorNordberg, E. K.en
dc.contributor.authorKarur, H. R.en
dc.contributor.authorShukla, Mauliken
dc.contributor.authorSoneja, J.en
dc.contributor.authorTian, Y.en
dc.contributor.authorXue, T.en
dc.contributor.authorYoo, H.en
dc.contributor.authorZhang, F.en
dc.contributor.authorDharmanolla, C.en
dc.contributor.authorDongre, N. V.en
dc.contributor.authorGillespie, J. J.en
dc.contributor.authorHamelius, J.en
dc.contributor.authorHance, M.en
dc.contributor.authorHuntington, K. I.en
dc.contributor.authorJukneliene, D.en
dc.contributor.authorKoziski, J.en
dc.contributor.authorMackasmiel, L.en
dc.contributor.authorMane, S. P.en
dc.contributor.authorNguyen, V.en
dc.contributor.authorPurkayastha, A.en
dc.contributor.authorShallom, J.en
dc.contributor.authorYu, G.en
dc.contributor.authorGuo, Y.en
dc.contributor.authorGabbard, Joseph L.en
dc.contributor.authorHix, D.en
dc.contributor.authorAzad, A. F.en
dc.contributor.authorBaker, S. C.en
dc.contributor.authorBoyle, Stephen M.en
dc.contributor.authorKhudyakov, Y.en
dc.contributor.authorMeng, Xiang-Jinen
dc.contributor.authorRupprecht, C.en
dc.contributor.authorVinje, J.en
dc.contributor.authorCrasta, Oswald R.en
dc.contributor.authorCzar, M. J.en
dc.contributor.authorDickerman, Allan W.en
dc.contributor.authorEckart, J. D.en
dc.contributor.authorKenyon, R.en
dc.contributor.authorWill, R.en
dc.contributor.authorSetubal, Joao C.en
dc.contributor.authorSobral, Brunoen
dc.date.accessioned2019-04-19T18:32:02Zen
dc.date.available2019-04-19T18:32:02Zen
dc.date.issued2007-01en
dc.description.abstractThe PathoSystems Resource Integration Center (PATRIC) is one of eight Bioinformatics Resource Centers (BRCs) funded by the National Institute of Allergy and Infection Diseases (NIAID) to create a data and analysis resource for selected NIAID priority pathogens, specifically proteobacteria of the genera Brucella, Rickettsia and Coxiella, and corona-, calici- and lyssaviruses and viruses associated with hepatitis A and E. The goal of the project is to provide a comprehensive bioinformatics resource for these pathogens, including consistently annotated genome, proteome and metabolic pathway data to facilitate research into counter-measures, including drugs, vaccines and diagnostics. The project's curation strategy has three prongs: 'breadth first' beginning with whole-genome and proteome curation using standardized protocols, a 'targeted' approach addressing the specific needs of researchers and an integrative strategy to leverage high-throughput experimental data (e.g. microarrays, proteomics) and literature. The PATRIC infrastructure consists of a relational database, analytical pipelines and a website which supports browsing, querying, data visualization and the ability to download raw and curated data in standard formats. At present, the site warehouses complete sequences for 17 bacterial and 332 viral genomes. The PATRIC website (https://patric.vbi.vt.edu) will continually grow with the addition of data, analysis and functionality over the course of the project.en
dc.description.sponsorshipPHS HHS [HHSN266200400035C]en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1093/nar/gkl858en
dc.identifier.eissn1362-4962en
dc.identifier.issn0305-1048en
dc.identifier.pmid17142235en
dc.identifier.urihttp://hdl.handle.net/10919/89062en
dc.identifier.volume35en
dc.language.isoenen
dc.rightsCreative Commons Attribution-NonCommercial 2.0 Genericen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/2.0/en
dc.subjectmultiple sequence alignmenten
dc.subjectprotein familiesen
dc.subjectdatabaseen
dc.subjectinformationen
dc.subjectgenomesen
dc.subjectrecognitionen
dc.subjectprogramsen
dc.subjectdiseasesen
dc.titlePATRIC: The VBI PathoSystems Resource Integration Centeren
dc.title.serialNucleic Acids Researchen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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