Community Structure and Function of Amphibian Skin Microbes: An Experiment with Bullfrogs Exposed to a Chytrid Fungus

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dc.contributor.authorWalke, Jenifer B.en
dc.contributor.authorBecker, Matthew H.en
dc.contributor.authorLoftus, Stephen C.en
dc.contributor.authorHouse, Leanna L.en
dc.contributor.authorTeotonio, Thais L.en
dc.contributor.authorMinbiole, Kevin P. C.en
dc.contributor.authorBelden, Lisa K.en
dc.contributor.departmentBiological Sciencesen
dc.contributor.departmentStatisticsen
dc.date.accessioned2018-09-10T18:52:21Zen
dc.date.available2018-09-10T18:52:21Zen
dc.date.issued2015-10-07en
dc.description.abstractThe vertebrate microbiome contributes to disease resistance, but few experiments have examined the link between microbiome community structure and disease resistance functions. Chytridiomycosis, a major cause of amphibian population declines, is a skin disease caused by the fungus, Batrachochytrium dendrobatidis (Bd). In a factorial experiment, bullfrog skin microbiota was reduced with antibiotics, augmented with an anti-Bd bacterial isolate (Janthinobacterium lividum), or unmanipulated, and individuals were then either exposed or not exposed to Bd. We found that the microbial community structure of individual frogs prior to Bd exposure influenced Bd infection intensity one week following exposure, which, in turn, was negatively correlated with proportional growth during the experiment. Microbial community structure and function differed among unmanipulated, antibiotic-treated, and augmented frogs only when frogs were exposed to Bd. Bd is a selective force on microbial community structure and function, and beneficial states of microbial community structure may serve to limit the impacts of infection.en
dc.description.sponsorshipThis work was funded by the Virginia Tech Fralin Life Science Institute and the National Science Foundation (DEB-1136640 and CHE-0958973). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.en
dc.description.versionPublished versionen
dc.format.extent18 pagesen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationWalke JB, Becker MH, Loftus SC, House LL, Teotonio TL, Minbiole KPC, et al. (2015) Community Structure and Function of Amphibian Skin Microbes: An Experiment with Bullfrogs Exposed to a Chytrid Fungus. PLoS ONE 10(10): e0139848. doi:10.1371/journal.pone.0139848en
dc.identifier.doihttps://doi.org/10.1371/journal.pone.0139848en
dc.identifier.eissn1932-6203en
dc.identifier.issue10en
dc.identifier.othere0139848en
dc.identifier.pmid26445500en
dc.identifier.urihttp://hdl.handle.net/10919/84987en
dc.identifier.volume10en
dc.language.isoenen
dc.publisherPLOSen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectCommensalismen
dc.subjectcommunity dynamicsen
dc.subjectdisease ecologyen
dc.subjecthost–parasite interactionsen
dc.subjectmutualismen
dc.titleCommunity Structure and Function of Amphibian Skin Microbes: An Experiment with Bullfrogs Exposed to a Chytrid Fungusen
dc.title.serialPLOS ONEen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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