The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation

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dc.contributor.authorKosch, Tiffany A.en
dc.contributor.authorTorres-Sánchez, Maríaen
dc.contributor.authorLiedtke, H. C.en
dc.contributor.authorSummers, Kyleen
dc.contributor.authorYun, Maximina H.en
dc.contributor.authorCrawford, Andrew J.en
dc.contributor.authorMaddock, Simon T.en
dc.contributor.authorAhammed, Md. S.en
dc.contributor.authorAraújo, Victor L. N.en
dc.contributor.authorBertola, Lorenzo V.en
dc.contributor.authorBucciarelli, Gary M.en
dc.contributor.authorCarné, Alberten
dc.contributor.authorCarneiro, Céline M.en
dc.contributor.authorChan, Kin O.en
dc.contributor.authorChen, Yingen
dc.contributor.authorCrottini, Angelicaen
dc.contributor.authorda Silva, Jessica M.en
dc.contributor.authorDenton, Robert D.en
dc.contributor.authorDittrich, Carolinen
dc.contributor.authorEspregueira Themudo, Gonçaloen
dc.contributor.authorFarquharson, Katherine A.en
dc.contributor.authorForsdick, Natalie J.en
dc.contributor.authorGilbert, Edwarden
dc.contributor.authorChe, Jingen
dc.contributor.authorKatzenback, Barbara A.en
dc.contributor.authorKotharambath, Ramachandranen
dc.contributor.authorLevis, Nicholas A.en
dc.contributor.authorMárquez, Robertoen
dc.contributor.authorMazepa, Gliben
dc.contributor.authorMulder, Kevin P.en
dc.contributor.authorMüller, Hendriken
dc.contributor.authorO’Connell, Mary J.en
dc.contributor.authorOrozco-terWengel, Pabloen
dc.contributor.authorPalomar, Gemmaen
dc.contributor.authorPetzold, Aliceen
dc.contributor.authorPfennig, David W.en
dc.contributor.authorPfennig, Karin S.en
dc.contributor.authorReichert, Michael S.en
dc.contributor.authorRobert, Jacquesen
dc.contributor.authorScherz, Mark D.en
dc.contributor.authorSiu-Ting, Karenen
dc.contributor.authorSnead, Anthony A.en
dc.contributor.authorStöck, Matthiasen
dc.contributor.authorStuckert, Adam M. M.en
dc.contributor.authorStynoski, Jennifer L.en
dc.contributor.authorTarvin, Rebecca D.en
dc.contributor.authorWollenberg Valero, Katharina C.en
dc.date.accessioned2024-11-04T13:30:49Zen
dc.date.available2024-11-04T13:30:49Zen
dc.date.issued2024-11-01en
dc.date.updated2024-11-03T04:18:24Zen
dc.description.abstractAmphibians represent a diverse group of tetrapods, marked by deep divergence times between their three systematic orders and families. Studying amphibian biology through the genomics lens increases our understanding of the features of this animal class and that of other terrestrial vertebrates. The need for amphibian genomic resources is more urgent than ever due to the increasing threats to this group. Amphibians are one of the most imperiled taxonomic groups, with approximately 41% of species threatened with extinction due to habitat loss, changes in land use patterns, disease, climate change, and their synergistic effects. Amphibian genomic resources have provided a better understanding of ontogenetic diversity, tissue regeneration, diverse life history and reproductive modes, anti-predator strategies, and resilience and adaptive responses. They also serve as essential models for studying broad genomic traits, such as evolutionary genome expansions and contractions, as they exhibit the widest range of genome sizes among all animal taxa and possess multiple mechanisms of genetic sex determination. Despite these features, genome sequencing of amphibians has significantly lagged behind that of other vertebrates, primarily due to the challenges of assembling their large, repeat-rich genomes and the relative lack of societal support. The emergence of long-read sequencing technologies, combined with advanced molecular and computational techniques that improve scaffolding and reduce computational workloads, is now making it possible to address some of these challenges. To promote and accelerate the production and use of amphibian genomics research through international coordination and collaboration, we launched the Amphibian Genomics Consortium (AGC, https://mvs.unimelb.edu.au/amphibian-genomics-consortium ) in early 2023. This burgeoning community already has more than 282 members from 41 countries. The AGC aims to leverage the diverse capabilities of its members to advance genomic resources for amphibians and bridge the implementation gap between biologists, bioinformaticians, and conservation practitioners. Here we evaluate the state of the field of amphibian genomics, highlight previous studies, present challenges to overcome, and call on the research and conservation communities to unite as part of the AGC to enable amphibian genomics research to “leap” to the next level.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationBMC Genomics. 2024 Nov 01;25(1):1025en
dc.identifier.doihttps://doi.org/10.1186/s12864-024-10899-7en
dc.identifier.urihttps://hdl.handle.net/10919/121523en
dc.language.isoenen
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.holderThe Author(s)en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.titleThe Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservationen
dc.title.serialBMC Genomicsen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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