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Cross-metathesized polysaccharide derivatives and processes for preparing them

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dc.contributor.assigneeVirginia Tech Intellectual Properties, Inc.en
dc.contributor.authorEdgar, Kevin J.en
dc.contributor.authorMatson, John B.en
dc.contributor.authorMeng, Xiangtaoen
dc.contributor.inventorEdgar, Kevinen
dc.contributor.inventorMatson, John B.en
dc.contributor.inventorMeng, Xiangtaoen
dc.date.accessioned2021-03-18T20:03:47Zen
dc.date.available2021-03-18T20:03:47Zen
dc.date.filed2014-09-26en
dc.date.issued2020-08-11en
dc.date.updated2021-03-18T20:03:46Zen
dc.description.abstractMethods for the cross-metathesis of polysaccharides with one or more olefin-terminated side chains and cross-metathesized products are described. In an exemplary embodiment, a method for the synthesis of cellulose ω-carboxyesters via olefin cross-metathesis is described. Conditions of the reactions were relatively mild and the olefin-substituted polysaccharides and the appropriate monomeric olefin partners appear to follow Grubbs rules as summarized herein. The compounds and methods may be useful for structure-property studies, particularly those aimed at developing polymers for drug delivery, such as for controlled-release drug delivery systems, controlled-release coatings, increasing bioavailability of drugs, and maintaining drug supersaturation in the GI tract.en
dc.identifier.applicationnumber15025451en
dc.identifier.orcidEdgar, Kevin [0000-0002-9459-9477]en
dc.identifier.patentnumber10738134en
dc.identifier.urihttp://hdl.handle.net/10919/102747en
dc.publisherUS Patent Officeen
dc.rightsIn Copyright (InC)en
dc.rightsThis Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).en
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.cpcA61K47/38en
dc.subject.cpcC08B3/16en
dc.subject.cpcC08B3/00en
dc.subject.cpcC08B3/14en
dc.subject.cpcC08B37/0018en
dc.subject.cpcC08B37/0021en
dc.titleCross-metathesized polysaccharide derivatives and processes for preparing themen
dc.typePatenten
dc.type.patenttypeutilityen
pubs.organisational-group/Virginia Tech/Natural Resources & Environmenten
pubs.organisational-group/Virginia Tech/All T&R Facultyen
pubs.organisational-group/Virginia Tech/Natural Resources & Environment/Sustainable Biomaterialsen
pubs.organisational-group/Virginia Tech/Natural Resources & Environment/CNRE T&R Facultyen
pubs.organisational-group/Virginia Tech/University Research Institutes/Fralin Life Sciences/Durelle Scotten
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/University Research Institutes/Fralin Life Sciencesen
pubs.organisational-group/Virginia Tech/University Research Institutesen
pubs.patent-statusRegularen
pubs.start-date2020-08-11en

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