Evaluation of a micro-adsorption detector in liquid and gas chromatography
| dc.contributor.author | Stafford, David Todd | en |
| dc.contributor.department | Chemistry | en |
| dc.date.accessioned | 2019-07-03T18:08:53Z | en |
| dc.date.available | 2019-07-03T18:08:53Z | en |
| dc.date.issued | 1971 | en |
| dc.description.abstract | A study was made with the objectives: 1. Evaluation of a micro-adsorption detector for use in liquid chromatography. 2. Evaluation of a micro-adsorption detector for use in gas ch.ranatography. 3. Investigation of the micro-adsorption cell as a tool for screening chromatographic systems, in adsorption studies, and as a micro-calorimeter. The micro-adsorption detector was found to have sufficient sensitivity to detect nanogram quantities of a component in either a liquid or gaseous carrier, and to have a linear dynamic range of 10²-10³. These qualities, combined with the selectivity of the detector indicate its usefulness in both liquid and gas chromatographic operations. The major limitation to its use is the characteristic adsorption/desorption responsive curve, which requires increased column lengths or resolution over other detectors such as the UV detector. In addition a semi-quantitative correlation between MAD response and chromatographic retention times indicates that the detector has significant potential as a screening tool for separation systems. By means of a calibration apparatus the detector response was characterized in terms of heat flux and temperature differential, and heats of absorption were calculated at concentrations of 10⁻⁴- 10⁻⁶ molar. These compared favorably with those literature values which were available close to these concentrations. | en |
| dc.description.degree | Ph. D. | en |
| dc.format.extent | vii, 106 leaves | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.uri | http://hdl.handle.net/10919/91013 | en |
| dc.language.iso | en | en |
| dc.publisher | Virginia Polytechnic Institute and State University | en |
| dc.relation.isformatof | OCLC# 34178115 | en |
| dc.rights | In Copyright | en |
| dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | en |
| dc.subject.lcc | LD5655.V856 1971.S7 | en |
| dc.title | Evaluation of a micro-adsorption detector in liquid and gas chromatography | en |
| dc.type | Dissertation | en |
| dc.type.dcmitype | Text | en |
| thesis.degree.discipline | Chemistry | en |
| thesis.degree.grantor | Virginia Polytechnic Institute and State University | en |
| thesis.degree.level | doctoral | en |
| thesis.degree.name | Ph. D. | en |
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