Action at a distance for specific repression of the glpD and glpTQ genes, and organization of the glpEGR genes of Escherichia coli K-12

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dc.contributor.authorYang, Bingen
dc.contributor.committeechairLarson, Timothy J.en
dc.contributor.committeememberNiehaus, Walter G. Jr.en
dc.contributor.committeememberSitz, Thomas O.en
dc.contributor.committeememberGregory, Eugene M.en
dc.contributor.committeememberBoyle, Stephen M.en
dc.contributor.departmentBiochemistryen
dc.date.accessioned2014-03-14T21:20:20Zen
dc.date.adate2006-10-04en
dc.date.available2014-03-14T21:20:20Zen
dc.date.issued1997en
dc.date.rdate2006-10-04en
dc.date.sdate2006-10-04en
dc.description.abstractAerobic sn-glycero13-phosphate (glycerol-P) dehydrogenase is a cytoplasmic membrane-associated respiratory enzyme encoded by the g/pD gene of Escherichia coli. The divergently transcribed glpACB and glpTQ operons encode the subunits of the anaerobic glycerol-P dehydrogenase, glycerol-P transporter, and glycerophosphodiesterase, respectively. The glpD operon is controlled by cooperative binding of glp repressor (GlpR) to tandem operators that cover the -10 promoter element and 30 bp downstream of the transcription start site. The glpACB-glpTQ operons operons are controlled by GlpR binding to operators that overlap the glpA promoter elements. In this study, two additional operators were identified within the glpD structural gene, and three additional operators were identified within the glp T structural gene.en
dc.description.degreePh. D.en
dc.format.extentxi, 138 leavesen
dc.format.mediumBTDen
dc.format.mimetypeapplication/pdfen
dc.identifier.otheretd-10042006-143914en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-10042006-143914/en
dc.identifier.urihttp://hdl.handle.net/10919/39623en
dc.language.isoenen
dc.publisherVirginia Techen
dc.relation.haspartLD5655.V856_1997.Y364.pdfen
dc.relation.isformatofOCLC# 36762698en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.lccLD5655.V856 1997.Y364en
dc.titleAction at a distance for specific repression of the glpD and glpTQ genes, and organization of the glpEGR genes of Escherichia coli K-12en
dc.typeDissertationen
dc.type.dcmitypeTexten
thesis.degree.disciplineBiochemistryen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.leveldoctoralen
thesis.degree.namePh. D.en

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