This research attempts to evaluate temporary urban regeneration potential by integrating two systems that make up an interim intervention which addresses an observed problem. The research proposes a systematic approach for a multi-system life cycle assessment model which lays out the process of working with two separate systems to provide a pathway for temporary urban development strategies. To achieve this, the research starts with identifying parameters of temporary urban regeneration through a systematic review of the literature. Key parameters are categorized based on objectives, indicators, as well as, physical characteristics of the literature explored case studies. Then, the findings are utilized to guide the proposed model of connecting two given systems to assess their joint impacts on a temporary urban regeneration system. The proposed MSLCA framework utilizes a holistic modeling structure with a process to integrate and analyze separate systems and quantify results for overall sustainability performance. Finally, the model is used to evaluate a case study involving two systems that address observed problems and provide urban services. The results explore the environmental impacts of the proposed intervention and highlight the effects of individual components on both systems. Through the implementation of the model, decisions on temporary urban intervention are guided by hotspots in the results. The findings reveal an opportunity for future research to expand the model's application to other processes and further its scope beyond environmental indicators. Subsequent studies can investigate opportunities for a holistic approach that includes economic and social aspects.