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Controlled cross circulation: effects on donor hemodynamics
Controlled cross circulation was performed in six pairs of dogs to assess
hemodynamic changes in the donor dog. Cardiopulmonary bypass was performed
for 45 minutes, with an aortic cross clamp time of 3 5 minutes. Anesthesia was
maintained in the donor dog with 1.8% end-tidal isoflurane. Parameters before and
after controlled cross circulation were compared using a Wilcoxon Signed Rank
Donor left ventricular dP/dt max, pulmonary capillary wedge pressure,
blood volume, systemic vascular resistance, heart rate, total protein, platelet count,
and white blood cell count did not change significantly. Donor cardiac output, end
diastolic volume, central venous pressure, stroke volume, mean arterial blood
pressure, and packed cell volume all decreased significantly (p