Spatial Organization of Chromosomes in Malaria Mosquitoes

Abstract

Malaria mosquitoes are vectors of dangerous human diseases and a model system for investigations of chromosome evolution, heterochromatin organization, and nuclei architecture in the cells of the reproductive system. Investigations of nurse cells chromosomes are aimed at understanding of mechanisms that cause interspecies differences in the nuclear spatial organization in these cells. One of the most important tasks of this research is the undestanding of molecular organization of the chromosome regions that are attached to the nuclear envelope. In the present review, the recent achievements in this field of research are described and unsolved problems of the spatial chromosome organization are identified.