Skeletal muscle stem cells from animals I. Basic cell biology.
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Skeletal muscle stem cells from food-producing animals are of interest to agricultural life scientists seeking to develop a better understanding of the molecular regulation of lean tissue (skeletal muscle protein hypertrophy) and intramuscular fat (marbling) development. Enhanced understanding of muscle stem cell biology and function is essential for developing technologies and strategies to augment the metabolic efficiency and muscle hypertrophy of growing animals potentially leading to greater efficiency and reduced environmental impacts of animal production, while concomitantly improving product uniformity and consumer acceptance and enjoyment of muscle foods.
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Talmadge, Robert J; Otis, Jeffrey S; Rittler, Matthew R; Garcia, Nicole D; Spencer, Shelly R; Lees, Simon J; Naya, Francisco J (2004-07-28)Background The calcium activated protein phosphatase 2B, also known as calcineurin, has been implicated as a cell signaling molecule involved with transduction of physiological signals (free cytosolic Ca2+) into molecular ...
Effects of Reduced Muscle Glycogen on Sarcoplasmic Reticulum (SR), Muscle and Exercise Performance Batts, Timothy W. (Virginia Tech, 2002-04-19)Fatigue during exercise is associated with reduced muscle glycogen. However, evidence linking glycogen content to fatigue is lacking. In this study we examined whether reduced muscle glycogen content limited SR function ...
Green tea extract and epigallocatechin gallate decrease muscle pathology and NF-ÎºB immunostaining in regenerating muscle fibers of mdx mice Evans, Nicholas Paul (Virginia Tech, 2009-09-25)Duchenne muscular dystrophy is a debilitating genetic disorder characterized by severe muscle wasting and early death in affected boys. The primary cause of this disease is mutations in the dystrophin gene resulting in the ...