Cyclohexyl Ketone Inhibitors of Pin1 Dock in a Trans-Diaxial Cyclohexane Conformation
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Date
2012-09-19
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PLOS
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Keywords
alzheimers gamma-secretase, cis/trans isomerase pin1, substrate recognition, proline isomerization, prolyl, cyclophilin, mechanism, catalysis, inactivation, calcineurin