Review—Prospects in Cancer Diagnosis: Exosome-Chip for Liquid Biopsy

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dc.contributor.authorKhondakar, Kamil Rezaen
dc.contributor.authorAtaei Kachouei, Matinen
dc.contributor.authorErukainure, Frank Efeen
dc.contributor.authorAli, Md Azaharen
dc.date.accessioned2023-11-27T13:10:32Zen
dc.date.available2023-11-27T13:10:32Zen
dc.date.issued2023-12-01en
dc.date.updated2023-11-27T11:57:46Zen
dc.description.abstractA liquid biopsy combined with an exosome-chip (EC) is an important detection tool for early cancer diagnosis. Exosomes have a crucial function in the exchange of information between cells and are present in biological fluids. ECs are miniaturized microfluidic devices designed to isolate, capture, and analyze exosomes for analysis of patient samples. Such devices offer on-chip detection, high-throughput analysis, and multiplex measurements. Further, these chips can integrate with electrochemical and optical detectors, and mass spectrometry enabling comprehensive studies of diseases. This review will cover the outlook on chip-based diagnostics for liquid biopsy, detection, and isolation of exosomes to support cancer diagnostics.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1149/2754-2726/ad08d7en
dc.identifier.eissn2754-2726en
dc.identifier.issn2754-2726en
dc.identifier.issue4en
dc.identifier.orcidErukainure, Frank [0000-0002-7640-391X]en
dc.identifier.urihttp://hdl.handle.net/10919/116688en
dc.identifier.volume2en
dc.language.isoenen
dc.publisherThe Electrochemical Societyen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subject3401 Analytical Chemistryen
dc.subject34 Chemical Sciencesen
dc.subjectPreventionen
dc.subjectBiotechnologyen
dc.subjectCanceren
dc.subjectBioengineeringen
dc.subject4 Detection, screening and diagnosisen
dc.subject4.1 Discovery and preclinical testing of markers and technologiesen
dc.titleReview—Prospects in Cancer Diagnosis: Exosome-Chip for Liquid Biopsyen
dc.title.serialECS Sensors Plusen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciencesen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/Biological Systems Engineeringen
pubs.organisational-group/Virginia Tech/Graduate studentsen
pubs.organisational-group/Virginia Tech/Graduate students/Doctoral studentsen

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