Possible thermoregulatory contributions of plasma B-endorphin during prolonged exercise in humans
| dc.contributor.author | Kelso, Thomas Benton | en |
| dc.contributor.department | Education | en |
| dc.date.accessioned | 2017-03-09T21:35:16Z | en |
| dc.date.available | 2017-03-09T21:35:16Z | en |
| dc.date.issued | 1983 | en |
| dc.description.abstract | Six adult male volunteers of similar body composition and physical fitness were tested to determine plasma immunoreactive β-endorphin (Piβ-EN) response under three conditions of exercise thermoregulatory stress. The experimental protocol consisted of 120 min of stationary upright cycling at 50% Vo₂max under conditions of neutral (24ºC, 50% RH)/euhydration (NE), hot (35°C, 50% RH)/euhydration (HE), and hot/dehydration (HD). Piβ-EN was measured by radioimmunoassay at -30 min, 0 min, and at 15 min intervals thereafter. Change in plasma volume (ΔPV) was measured to determine its effect on Piβ-EN concentration. Preexercise Piβ-EN levels averaged 23.7 ± 2.6 pg•ml⁻¹ in all conditions. The greatest Piβ-EN response occurred at 105 min in HD conditions when levels rose to 43.2 ± 6.9 pg•ml⁻¹. Exercise in HD and HE conditions resulted in significantly (p < 0.05) elevated Piβ-EN above levels observed in NE. ΔPV did not account for more than 10% of Piβ-EN changes at any interval. The Piβ-EN response pattern closely resembled rectal temperature changes in all conditions. These data suggest that conditions of increasing exercise thermoregulatory stress are associated with increasing peripheral β-endorphin concentration. | en |
| dc.description.degree | Master of Science | en |
| dc.format.extent | x, 141 leaves | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.uri | http://hdl.handle.net/10919/76020 | en |
| dc.language.iso | en_US | en |
| dc.publisher | Virginia Polytechnic Institute and State University | en |
| dc.relation.isformatof | OCLC# 10748524 | en |
| dc.rights | In Copyright | en |
| dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | en |
| dc.subject.lcc | LD5655.V855 1983.K458 | en |
| dc.subject.lcsh | Exercise tests | en |
| dc.subject.lcsh | Body temperature -- Regulation | en |
| dc.title | Possible thermoregulatory contributions of plasma B-endorphin during prolonged exercise in humans | en |
| dc.type | Thesis | en |
| dc.type.dcmitype | Text | en |
| thesis.degree.discipline | Education | en |
| thesis.degree.grantor | Virginia Polytechnic Institute and State University | en |
| thesis.degree.level | masters | en |
| thesis.degree.name | Master of Science | en |
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